Evidence map›Paper›PMID 29575682›Full record

ArticleCNS neuroscience & therapeutics2018

Functional outcome and service engagement in major depressive disorder with psychotic features: comparisons with schizophrenia, schizoaffective disorder and bipolar disorder in a 6-year follow-up of the Cavan-Monaghan First Episode Psychosis Study (CAMFEPS).

Tara Kingston, Paul J Scully, David J Browne, Patrizia A Baldwin, Anthony Kinsella, Eadbhard O'Callaghan, Vincent Russell, John L Waddington

Abstract readMulticenter Study
In one paragraph

Article in CNS neuroscience & therapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Development of an Interprofessional Psychosocial Interventions Framework.International journal of environmental research and public health · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tara KingstonCavan-Monaghan Mental Health Service, St. Davnet's Hospital, Monaghan, Ireland.
Paul J ScullyCavan-Monaghan Mental Health Service, St. Davnet's Hospital, Monaghan, Ireland.
David J BrowneCavan-Monaghan Mental Health Service, St. Davnet's Hospital, Monaghan, Ireland.
Patrizia A BaldwinCavan-Monaghan Mental Health Service, St. Davnet's Hospital, Monaghan, Ireland.
Anthony KinsellaMolecular & Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.
Eadbhard O'CallaghanDETECT Early Psychosis Service, Blackrock, Co. Dublin, Ireland.
Vincent RussellCavan-Monaghan Mental Health Service, St. Davnet's Hospital, Monaghan, Ireland.
John L WaddingtonCavan-Monaghan Mental Health Service, St. Davnet's Hospital, Monaghan, Ireland.ORCID 0000-0003-3755-3373

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWhile long-term outcome following a first psychotic episode is well studied in schizophrenia (SZ), schizoaffective disorder (SA), and bipolar disorder (BD), major depressive disorder with psychotic features (MDDP) has received less investigation. This study compares MDDP with SZ, SA, and BD at 6-year follow-up.

methodsAt 6 years after a first psychotic episode, follow-up data on psychopathology, functioning, quality of life, and service engagement were obtained for 27 cases of MDDP in comparison to 60 SZ, 27 SA, and 35 BD.

resultsPositive psychotic symptoms were less prominent in MDDP and BD than in SZ and SA. Negative symptoms, impaired functioning, and reduction in objectively determined quality of life were less prominent in MDDP and BD, intermediate in SA and most prominent in SZ. However, subjectively determined quality of life was indistinguishable across diagnoses. Service engagement was highest for MDDP, intermediate for SA and BD, and lowest for SZ.

conclusionsAt 6-year follow-up, these diagnoses are characterized by quantitative rather than qualitative differences in psychopathology, functionality, quality of life, and service engagement, with considerable overlap between them. These findings suggest that MDDP should join SZ, SA, and BD in a milieu of psychosis that transcends arbitrary boundaries.

Indexed as

Bipolar DisorderDisease ManagementSchizophrenic PsychologyAdultAgedFemaleHumansIrelandLongitudinal StudiesMaleMiddle AgedPsychotic DisordersQuality of LifeRural PopulationSchizophrenia6-year follow-upfunctional outcomemajor depressive disorder with psychotic featuresquality of lifeservice engagement

Identifiers

PMID29575682
PMCPMC6490013

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.