ArticleJournal of biophotonics2018
Assessing glycation-mediated changes in human cortical bone with Raman spectroscopy.
Article in Journal of biophotonics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed, 61 citations in OpenAlex.
- Collagen-Related Viscoelasticity as a Metric for Fracture Assessment in Cortical Bone.Annals of biomedical engineering · 2026Article
- Effect of Canagliflozin Pretreatment on the Efficacy of Insulin Therapy to Rescue Type 1 Diabetes-Related Bone Fragility in Male Mice.Calcified tissue international · 2026Article
- Advanced glycation end-product adducts alter the bone collagen network and human cortical bone fracture resistance.JBMR plus · 2026Article
- Rotator Cuff Tear-induced Changes in Tendon Structure and Mechanics Measured by Quantitative Magnetic Resonance Imaging.Annals of biomedical engineering · 2025Article
- Article
- Diabetic bone fragility through advanced glycation end product-collagen axis: Mechanisms and therapy of sodium glucose cotransporter 2 inhibitors.World journal of diabetes · 2025Review
- Glycoxidation of the bone matrix modulates mineralization.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025Article
- Prediction of biomechanical properties of ex vivo human femoral cortical bone using Raman spectroscopy and machine learning algorithms.Bone reports · 2025Article
- The sex-specific effects of RAGE signaling and type 2 diabetes on mouse cortical bone mechanics, structure, and material properties.Mechanobiology in medicine · 2025Article
- Fecal microbiota transplantation in mice improves bone material properties through altered mineral quality.JBMR plus · 2025Article
- Potential preventive effects of angiotensin-(1-7) on bone matrix quality in diabetic rats through modulation of the organic matrix.Joint diseases and related surgery · 2025Article
- Article
- Optimizing number of Raman spectra using an artificial neural network guided Monte Carlo simulation approach to analyze human cortical bone.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy · 2025Article
- Long-duration type 1 diabetes is associated with deficient cortical bone mechanical behavior and altered matrix composition in human femoral bone.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024Article
- Evaluation of the effect of tartrazine on the offspring rats in an in vivo experimental model.Food science & nutrition · 2024Article
- Impact of heavy alcohol consumption on cortical bone mechanical properties in male rhesus macaques.Bone · 2024Article
- Microbiome-induced Increases and Decreases in Bone Tissue Strength can be Initiated After Skeletal Maturity.bioRxiv : the preprint server for biology · 2024Article
- Physicochemical understanding of biomineralization by molecular vibrational spectroscopy: From mechanism to nature.Exploration (Beijing, China) · 2023Review
- Review
- Zucker Diabetic-Sprague Dawley Rats Have Impaired Peri-Implant Bone Formation, Matrix Composition, and Implant Fixation Strength.JBMR plus · 2023Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Establishing a non-destructive method for spatially assessing advanced glycation end-products (AGEs) is a potentially useful step toward investigating the mechanistic role of AGEs in bone quality. To test the hypothesis that the shape of the amide I in the Raman spectroscopy (RS) analysis of bone matrix changes upon AGE accumulation, we incubated paired cadaveric cortical bone in ribose or glucose solutions and in control solutions for 4 and 16 weeks, respectively, at 37°C. Acquiring 10 spectra per bone with a 20X objective and a 830 nm laser, RS was sensitive to AGE accumulation (confirmed by biochemical measurements of pentosidine and fluorescent AGEs). Hyp/Pro ratio increased upon glycation using either 0.1 M ribose, 0.5 M ribose or 0.5 M glucose. Glycation also decreased the amide I sub-peak ratios (cm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.