Evidence map›Paper›PMID 29575339›Full record

ArticleAddiction (Abingdon, England)2018

Treatment response and non-response in CBT and Network Support for alcohol disorders: targeted mechanisms and common factors.

Mark D Litt, Ronald M Kadden, Howard Tennen

Open access · greenAbstract read
In one paragraph

Article in Addiction (Abingdon, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mark D LittUConn Health, Farmington, CT, USA.ORCID 0000-0002-8319-6090
Ronald M KaddenUConn Health, Farmington, CT, USA.
Howard TennenUConn Health, Farmington, CT, USA.
UConn Health · US

Funding

Network Support for Alcohol Treatment: Mechanisms and EffectivenessR01AA012827 · NIAAA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI LITT, MARK D. · 2002 to 2013
$5.6M
Individualized Assessment and Treatment Program for Alcoholism: Treatment and MechanismsR01AA024729 · NIAAA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI LITT, MARK D. · 2016 to 2020
$3.0M
NIAAA NIH HHS R01 AA012827NIAAA NIH HHS R01 AA024729
6 · The paper itself

Abstract

aimsTo determine whether mechanisms of drinking behavior change that are targeted by specific treatments mediate the effects of Packaged Cognitive Behavior Therapy (PCBT) and Network Support (NS) on abstinence rates throughout 27 months.

designSecondary analysis of data from two Network Support Project randomized clinical trials, in which participants were assigned to either a case management control treatment (control) or NS treatment in trial 1, or to PCBT or NS treatment in trial 2.

settingAn out-patient substance abuse treatment site at a university medical center in the United States.

participantsA total of 249 men and 154 women (n = 403) with alcohol use disorder. MEASUREMENTS: The primary outcome was membership in a treatment responder class determined by growth mixture modeling (GMM) of monthly proportion days abstinent (PDA) to 27 months. Key predictors of responder class membership included network change variables, and changes in coping scores and self-efficacy.

findingsGMM analyses indicated that a three-class solution provided the best fit to the data: a treatment responder class comprising almost 55% of patients, a late relapsing class that showed post-treatment gains followed by a return to baseline drinking (12.7% of patients) and a non-responder class (32% of patients). Analyses indicated that treatment effects on responder class membership were moderated by baseline drinking (P < 0.001). PCBT effects were mediated by changes in coping scores (P < 0.05). NS treatment effects were also mediated by coping change, as well as by increases in self-efficacy and in number of abstinent friends (P < 0.05).

conclusionsLong-term success in Packaged Cognitive Behavior Therapy and Network Support treatments for alcohol use disorder appears to be mediated by both general mechanisms (developing coping skills and self-efficacy) and treatment-targeted mechanisms (developing network strategies that emphasize social support and avoiding friends who drink).

Indexed as

Social EnvironmentSocial NetworkingAdaptation, PsychologicalAdolescentAdultAgedAged, 80 and overAlcohol AbstinenceAlcoholismAmbulatory CareCase ManagementCognitive Behavioral TherapyCombined Modality TherapyFemaleHumansMaleAlcohol treatmentcognitive behavior therapycommon factorscoping skillsNetwork Supportself-efficacytreatment mechanisms

Identifiers

PMID29575339
PMCPMC6043382
OpenAlexW2793484289

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.