Evidence map›Paper›PMID 29575254›Full record

Trial reportCancer science2018

Phase II study of adjuvant chemotherapy with paclitaxel and nedaplatin for uterine cervical cancer with lymph node metastasis.

Munetaka Takekuma, Mototsugu Shimokawa, Shin Nishio, Hideo Omi, Tsutomu Tabata, Yuji Takei, Kaei Nasu, Yoshiyuki Takahashi, Shinji Toyota, Yoshikazu Ichikawa and 6 more

Open access · goldAbstract readClinical Trial, Phase II
In one paragraph

Trial report in Cancer science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Observational
  7. Review
  8. Article
  9. Review
  10. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 15 institutions in 1 country.

Munetaka TakekumaDepartment of Gynecologic Oncology, Shizuoka Cancer Center, Shizuoka, Japan.ORCID http://orcid.org/0000-0002-0807-1845
Mototsugu ShimokawaCancer Biostatistics Laboratory, Clinical Research Institute, National Kyusyu Cancer Center, Fukuoka, Japan.
Shin NishioDepartment of Obstetrics and Gynecology, Kurume University School of Medicine, Fukuoka, Japan.ORCID http://orcid.org/0000-0003-2526-630X
Hideo OmiDepartment of Obstetrics and Gynecology, Iwate Medical University Hospital, Iwate, Japan.
Tsutomu TabataDepartment of Obstetrics and Gynecology, Mie University Hospital, Mie, Japan.
Yuji TakeiDepartment of Obstetrics and Gynecology, Jichi Medical University, Tochigi, Japan.
Kaei NasuDepartment of Obstetrics and Gynecology, Oita University Faculty of Medicine, Oita, Japan.
Yoshiyuki TakahashiDepartment of Obstetrics and Gynecology, Okinawa Chubu Hospital, Okinawa, Japan.
Shinji ToyotaDepartment of Obstetrics and Gynecology, Nara Prefecture General Medical Center, Nara, Japan.
Yoshikazu IchikawaDepartment of Obstetrics and Gynecology, Japanese Red Cross Shizuoka Hospital, Shizuoka, Japan.
Atsushi ArakawaDepartment of Obstetrics and Gynecology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Fuminori ItoDepartment of Obstetrics and Gynecology, Nara Medical University, Nara, Japan.
Hiroshi TsubamotoDepartment of Obstetrics and Gynecology, Hyogo College of Medicine, Hyogo, Japan.
Taisuke MoriDepartment of Obstetrics and Gynecology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Yasuyuki HirashimaDepartment of Gynecologic Oncology, Shizuoka Cancer Center, Shizuoka, Japan.
Kimihiko ItoDepartment of Obstetrics and Gynecology, Kansai Rosai Hospital, Hyogo, Japan.
Shizuoka Cancer Center · JPHyogo Medical University · JPIwate Medical University · JPJichi Medical University · JPKansai Rosai Hospital · JPKurume University · JPKyoto Prefectural University of Medicine · JPMie University Hospital · JPNagoya City University · JPNara Medical University · JPNara Prefecture General Medical CenterNational Hospital Organization Kyushu Cancer Center · JPOita University · JPOkinawa Prefectural Chubu Hospital · JPShizuoka Red Cross Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this phase II trial was to assess the efficacy and toxicity of paclitaxel and nedaplatin (TN) as the initial postoperative adjuvant chemotherapy for uterine cervical cancer with lymph node metastases (LNM). Patients with FIGO stage IB1-IIA2 squamous cell carcinoma of the uterine cervix were enrolled. Histological confirmation of LNM was mandatory. Intravenous paclitaxel at 175 mg/m

Indexed as

AdultAntineoplastic Combined Chemotherapy ProtocolsCarcinoma, Squamous CellChemoradiotherapyChemotherapy, AdjuvantFemaleHumansLymphatic MetastasisMiddle AgedNeoplasm Recurrence, LocalOrganoplatinum CompoundsPaclitaxelUterine Cervical NeoplasmsnedaplatinOrganoplatinum CompoundsPaclitaxelcervical cancerpaclitaxel and nedaplatinphase II studypostoperative adjuvant therapysystemic chemotherapy

Identifiers

PMID29575254
PMCPMC5980304
OpenAlexW2791185511

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.