Evidence map›Paper›PMID 29575090›Full record

Trial reportJournal of orthopaedic research : official publication of the Orthopaedic Research Society2018

Gait mechanics and tibiofemoral loading in men of the ACL-SPORTS randomized control trial.

Jacob J Capin, Ashutosh Khandha, Ryan Zarzycki, Amelia J H Arundale, Melissa L Ziegler, Kurt Manal, Thomas S Buchanan, Lynn Snyder-Mackler

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Gait Mechanics in Women of the ACL-SPORTS Randomized Control Trial: Interlimb Symmetry Improves Over Time Regardless of Treatment Group.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2019
    Trial
  5. Article
  6. Preoperative and Post-Rehabilitation Predictors of Gait Biomechanics Six Months After Total Knee Arthroplasty.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Secondary Anterior Cruciate Ligament Injury Prevention Training in Athletes: What Is the Missing Link?International journal of environmental research and public health · 2023
    Review
  12. Article
  13. Knee joint biomechanics during gait improve from 3 to 6 months after anterior cruciate ligament reconstruction.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Sex and mechanism of injury influence knee joint loading symmetry during gait 6 months after ACLR.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jacob J CapinBiomechanics and Movement Science, University of Delaware, Newark, Delaware.ORCID 0000-0001-9361-3700
Ashutosh KhandhaBiomedical Engineering, University of Delaware, Newark, Delaware.ORCID 0000-0001-6003-3881
Ryan ZarzyckiBiomechanics and Movement Science, University of Delaware, Newark, Delaware.
Amelia J H ArundaleBiomechanics and Movement Science, University of Delaware, Newark, Delaware.
Melissa L ZieglerBiostatistics Core, College of Health Sciences, University of Delaware, Newark, Delaware.
Kurt ManalMechanical Engineering, University of Delaware, Newark, Delaware.
Thomas S BuchananBiomedical Engineering, University of Delaware, Newark, Delaware.
Lynn Snyder-MacklerBiomechanics and Movement Science, University of Delaware, Newark, Delaware.

Funding

Subproject Title: Clinical Research Education, Mentoring and Career Development CoreU54GM104941 · NIGMS · UNIVERSITY OF DELAWARE · PI LEE M PACHTER · 2013 to 2026
$60.5M
Pilot Project ProgramP30GM103333 · NIGMS · UNIVERSITY OF DELAWARE · PI BUCHANAN, THOMAS S · 2012 to 2016
$5.7M
Dynamic Stability in the ACL Injured KneeR37HD037985 · NICHD · UNIVERSITY OF DELAWARE · PI GRAVARE SILBERNAGEL, KARIN M E · 2012 to 2021
$4.2M
PT/PHD Predoctoral Training Program Diversity SupplementT32HD007490 · NICHD · UNIVERSITY OF DELAWARE · PI DARCY S. REISMAN · 1996 to 2026
$3.7M
CAN NEUROMUSCULAR TRAINING ALTER MOVEMENT PATTERNS?R01AR048212 · NIAMS · UNIVERSITY OF DELAWARE · PI SNYDER-MACKLER, LYNN · 2005 to 2015
$3.6M
ACL Injured Knee: MRI and Biomechanical ModelingR01AR046386 · NIAMS · UNIVERSITY OF DELAWARE · PI BUCHANAN, THOMAS S · 1999 to 2011
$2.8M
ACL Reconstructed Knee: qMRI and Biomechanical ModelingR01HD087459 · NICHD · UNIVERSITY OF DELAWARE · PI BUCHANAN, THOMAS S · 2016 to 2020
$1.8M
Eunice Kennedy Shriver National Institute of Child Health and Human Development R01-HD087459Eunice Kennedy Shriver National Institute of Child Health and Human Development R37-HD037985Eunice Kennedy Shriver National Institute of Child Health and Human Development T32-HD00749Foundation for Physical Therapy Promotion of Doctoral Studies (PODS I) ScholarshipNIAMS NIH HHS R01 AR046386NIAMS NIH HHS R01 AR048212NIAMS NIH HHS R01-AR048212NICHD NIH HHS R01 HD087459NICHD NIH HHS R37 HD037985NICHD NIH HHS T32 HD007490NIGMS NIH HHS P30 GM103333NIGMS NIH HHS P30-GM103333NIGMS NIH HHS U54 GM104941NIGMS NIH HHS U54-GM104941University of Delaware Doctoral Fellowship Award (GRAD 112114)
6 · The paper itself

Abstract

The risk for post-traumatic osteoarthritis is elevated after anterior cruciate ligament reconstruction (ACLR), and may be especially high among individuals with aberrant walking mechanics, such as medial tibiofemoral joint underloading 6 months postoperatively. Rehabilitation training programs have been proposed as one strategy to address aberrant gait mechanics. We developed the anterior cruciate ligament specialized post-operative return-to-sports (ACL-SPORTS) randomized control trial to test the effect of 10 post-operative training sessions consisting of strength, agility, plyometric, and secondary prevention exercises (SAPP) or SAPP plus perturbation (SAPP + PERT) training on gait mechanics after ACLR. A total of 40 male athletes (age 23 ± 7 years) after primary ACLR were randomized to SAPP or SAPP + PERT training and tested at three distinct, post-operative time points: 1) after impairment resolution (Pre-training); 2) following 10 training sessions (Post-training); and 3) 2 years after ACLR. Knee kinematic and kinetic variables as well as muscle and joint contact forces were calculated via inverse dynamics and a validated electromyography-informed musculoskeletal model. There were no significant improvements from Pre-training to Post-training in either intervention group. Smaller peak knee flexion angles, extension moments, extensor muscle forces, medial compartment contact forces, and tibiofemoral contact forces were present across group and time, however the magnitude of interlimb differences were generally smaller and likely not meaningful 2 years postoperatively. Neither SAPP nor SAPP + PERT training appears effective at altering gait mechanics in men in the short-term; however, meaningful gait asymmetries mostly resolved between post-training and 2 years after ACLR regardless of intervention group. © 2018 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:2364-2372, 2018.

Indexed as

Anterior Cruciate Ligament ReconstructionGaitAdolescentAdultAnterior Cruciate Ligament InjuriesAthletesBiomechanical PhenomenaElectromyographyFemurHumansKnee JointMaleOsteoarthritisProspective StudiesReturn to SportStress, MechanicalACL-SPORTS Traininganterior cruciate ligament (ACL)gait biomechanicsmusculoskeletal modelingrehabilitation

Identifiers

PMID29575090
PMCPMC6157011

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.