ArticleJournal of clinical laboratory analysis2018
Safety and efficacy of enhanced recovery after surgery (ERAS) programs in patients undergoing hepatectomy: A prospective randomized controlled trial.
Article in Journal of clinical laboratory analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Specific Items of Enhanced Recovery After Surgery for Liver Surgery in Cirrhotic Patients: A Systematic Review.World journal of surgery · 2025Pooled it
- Impact of enhanced recovery pathways on patient-reported outcomes after abdominal surgery: a systematic review.Surgical endoscopy · 2023Pooled it
- Enhanced Recovery After Surgery (ERAS) Reduces Hospital Costs and Improve Clinical Outcomes in Liver Surgery: a Systematic Review and Meta-Analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020Pooled it
- Article
- Non-placement of nasogastric tube versus early removal of nasogastric tube in the enhanced recovery after surgery of hepatocellular carcinoma: a case control study.Perioperative medicine (London, England) · 2026Article
- Effectiveness of enhanced recovery after surgery protocols in elderly patients undergoing major abdominal surgery: a systematic review and meta-analysis.Frontiers in surgery · 2026Review
- Defining benchmarks for postoperative mobilization based on the recommendations of the Enhanced Recovery After Surgery (ERAS) program for liver surgery: a prospective study.Surgical endoscopy · 2025Observational
- Enhanced recovery after surgery society's recommendations for liver surgery reduces non surgical complications.Scientific reports · 2025Article
- The effectiveness and outcomes of epidural analgesia in patients undergoing open liver resection: a propensity score matching analysis.BMC anesthesiology · 2024Observational
- Enhanced recovery after liver surgery in cirrhotic patients: a systematic review and meta-analysis.Perioperative medicine (London, England) · 2024Article
- Enhanced recovery after surgery care to reduce surgical site wound infection and postoperative complications for patients undergoing liver surgery.International wound journal · 2023Review
- Validation of the Enhanced Recovery after Surgery (ERAS) society recommendations for liver surgery: a prospective, observational study.Hepatobiliary surgery and nutrition · 2023Article
- Effect of digital three-dimensional reconstruction technique combined with indocyanine green (ICG) excretion test for precision hepatectomy in primary liver cancer.American journal of translational research · 2023Article
- Article
- Pain management after open liver resection: Procedure-Specific Postoperative Pain Management (PROSPECT) recommendations.Regional anesthesia and pain medicine · 2021Review
- Enhanced Recovery After Surgery in Patients With Hepatocellular Carcinoma Undergoing Laparoscopic Hepatectomy.Frontiers in surgery · 2021Article
- Impact of Enhanced Recovery After Surgery on Long-Term Outcomes and Postoperative Recovery in Patients Undergoing Hepatectomy: A Retrospective Cohort Study.Cancer management and research · 2021Article
- Surgical approach to solid pseudopapillary neoplasms of the proximal pancreas: minimally invasive vs. open.World journal of surgical oncology · 2019Article
- Analysis of the postoperative hemostatic profile of colorectal cancer patients subjected to liver metastasis resection surgery.World journal of clinical cases · 2019Article
- Enhanced recovery after surgery in liver resection: current concepts and controversies.Korean journal of anesthesiology · 2019Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimEnhanced recovery after surgery (ERAS) programs, following a variety of perioperative treatments with evidence-based medical evidence, has indicated its validity to accelerate rehabilitation in a wide variety of surgical procedures. This randomized controlled trial (RCT) study was implemented to verify the safety and efficacy of the perioperative effects in patients undergoing hepatectomy with ERAS or with conventional surgery (CS).
methodsFrom August 2016 to November 2017, according to the inclusion criteria, 160 patients with liver diseases were suitable for participating in this experiment. Patients before liver resection were randomized into ERAS group (n = 80) and CS group (n = 80), and then the outcome measures were compared between the two groups.
resultsEnhanced recovery after surgery group had significantly less complications than CS group (P = .009). Compared with CS group, patients in ERAS group had low peak of WBCs in postoperative day (POD1), ALT in POD1 and POD3 (P < .05), high value of ALB in POD3 and POD5 (P < .05), less pain and higher patient satisfaction (P < .001), earlier exhaust, oral feeding, ambulation and extubation time (P < .05),and also had less hospital stay and cost (P < .001). There were no significant differences in readmission rate (<30 days) between two groups (P = .772).
conclusionsEnhanced recovery after surgery programs applied to patients undergoing hepatectomy can safely and effectively relieve stress response, reduce the incidence of complications, improve patient satisfaction, accelerate patient recovery, reduce financial burden, and bring economic benefits.
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