Evidence map›Paper›PMID 29574676›Full record

ArticleOphthalmology and therapy2018

Ischemic Stroke Risk in Medicare Beneficiaries with Central Retinal Artery Occlusion: A Retrospective Cohort Study.

Dustin D French, Curtis E Margo, Paul B Greenberg

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ophthalmology and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 55 citations in OpenAlex.

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  19. [Nonaretritic central retinal artery occlusion as marker for the generalized vascular risk].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Dustin D FrenchDepartment of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. Dustin.French@northwestern.edu.ORCID http://orcid.org/0000-0003-4064-3206
Curtis E MargoDepartment of Ophthalmology, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
Paul B GreenbergDivision of Ophthalmology, Alpert Medical School, Brown University, Providence, RI, USA.
Brown University · USNorthwestern University · USUniversity of South Florida · US

Funding

Understanding Diabetic Eye Disease in the Underserved Using Health Data ExchangeR21EY024050 · NEI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI FRENCH, DUSTIN D. · 2014 to 2015
$417k
National Eye Institute 1R21EY024050-01A1NEI NIH HHS R21 EY024050
6 · The paper itself

Abstract

introductionTo determine the incidence of ischemic cerebral stroke in the 6-month periods preceding and following acute central retinal artery occlusion (CRAO) among Medicare beneficiaries.

methodsA retrospective cohort study with comparison group conducted for calendar year 2013. Patients with CRAO were identified through National Medicare limited inpatient and institutional outpatient datasets for emergency services using ICD-9-CM code for CRAO (362.31). Patients with hip fractures (ICD-9-CM 820-820.9) during the same time period served as controls. Interval incident rates of ischemic stroke were determined from time-coded diagnoses of CRAO and hip fracture (index date zero) to date of principal discharge diagnosis of ischemic stroke (ICD-9-CM 434) recorded in the Medicare inpatient dataset. Risk of stroke was examined by comparing incidence among the two cohorts preceding and following the sentinel events.

resultsThere were 3338 patients with CRAOs during 2013. The incidence of ischemic stroke peaked the second week following CRAO relative to patients with hip fracture (relative incidence = 33.1 [95% confidence interval 9.8-84.6]).

conclusionsMedicare beneficiaries who present to emergency rooms with CRAO or are hospitalized directly for this condition were at highest risk of ischemic stroke in the first 2 weeks following the ocular diagnosis. Patients with acute CRAO should be promptly evaluated for stroke and stroke prevention.

Indexed as

Central retinal artery occlusionIschemic strokeStroke risk

Identifiers

PMID29574676
PMCPMC5997602
OpenAlexW2792138839

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.