ArticleJournal of assisted reproduction and genetics2018
Outcome of immature oocytes collection of 119 cancer patients during ovarian tissue harvesting for fertility preservation.
Article in Journal of assisted reproduction and genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
19 citing papers in PubMed, 51 citations in OpenAlex.
- Clinical outcomes over 12 years: a comparative analysis of oocyte cryopreservation from controlled ovarian stimulation and in vitro maturation retrieved from ovarian tissue.Journal of ovarian research · 2025Article
- Nicotinamide mononucleotide protects ovarian function and oocyte developmental competence during chemotherapy.Journal of ovarian research · 2025Article
- REPRODUCTIVE HEALTH IN TRANS AND GENDER-DIVERSE PATIENTS: Gonadal tissue cryopreservation in transgender and gender-diverse people.Reproduction (Cambridge, England) · 2024Review
- Live birth after vitrification of oocytes from capacitation in vitro maturation.Journal of assisted reproduction and genetics · 2024Article
- Successful pregnancy using immature oocytes retrieved from resected borderline ovarian tumor: a case report and literature review.Contraception and reproductive medicine · 2024Article
- Factors associated with the collection of isolated immature oocytes during ovarian tissue cryopreservation.Journal of assisted reproduction and genetics · 2023Article
- Outcomes of Different In Vitro Maturation Procedures for Oocyte Cryopreservation for Fertility Preservation and yet Another Live Birth in a Cancer Patient.Life (Basel, Switzerland) · 2023Article
- The Late Effects of Cancer Treatment on Female Fertility and the Current Status of Fertility Preservation-A Narrative Review.Life (Basel, Switzerland) · 2023Review
- Installing oncofertility programs for breast cancer in limited versus optimum resource settings: Empirical data from 39 surveyed centers in Repro-Can-OPEN Study Part I & II.Journal of assisted reproduction and genetics · 2022Article
- In Vitro Maturation of Oocytes Retrieved from Ovarian Tissue: Outcomes from Current Approaches and Future Perspectives.Journal of clinical medicine · 2021Review
- Improved maturation competence of ovarian tissue oocytes using a biphasic in vitro maturation system for patients with gynecological malignancy: a study on sibling oocytes.Journal of assisted reproduction and genetics · 2021Article
- The usefulness of metaphase I oocytes in women who undergo controlled ovarian hyperstimulation for intracytoplasmic sperm injection.JBRA assisted reproduction · 2021Article
- Installing oncofertility programs for common cancers in optimum resource settings (Repro-Can-OPEN Study Part II): a committee opinion.Journal of assisted reproduction and genetics · 2021Article
- Human Ovarian Cortex biobanking: A Fascinating Resource for Fertility Preservation in Cancer.International journal of molecular sciences · 2020Review
- Cryopreservation of euploid blastocysts obtained after fertilization of in vitro matured ovarian tissue oocytes: a case report.Journal of assisted reproduction and genetics · 2020Article
- Fertility Preservation for Child and Adolescent Cancer Patients in Asian Countries.Frontiers in endocrinology · 2019Article
- Preservation of female fertility in humans and animal species.Animal reproduction · 2018Article
- Cryopreservation of Ovarian Tissue: Opportunities Beyond Fertility Preservation and a Positive View Into the Future.Frontiers in endocrinology · 2018Review
- IVM of human immature oocytes for infertility treatment and fertility preservation.Reproductive medicine and biologyReview
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeFew clinical options for fertility preservation are available to females with cancer, and data about clinical outcomes is limited. Potential supplementary approaches to fertility preservation include retrieval of immature oocytes followed by in vitro maturation (IVM) and storage. The aim of this study was to evaluate post-thawing outcomes of immature oocytes collected both by transvaginal aspiration and from excised ovarian tissue.
methodsWe conducted a retrospective cohort study of patients treated in a single tertiary center. We reviewed the records of 119 cancer patients who underwent ovarian tissue cryopreservation and immature oocyte harvesting for fertility preservation. All embryos and oocytes that were frozen and thawed were included in the study. Post-thawing outcomes were evaluated.
resultsThirty-five stored embryos from eight patients were thawed. Twenty-nine embryos survived (82% survival rate) and were transferred. Six oocytes were thawed, two oocytes survived, and no oocytes were fertilized. Only one PCOS patient became pregnant, resulting in the normal delivery of a healthy baby.
conclusionsAlthough a relatively high number of mature oocytes and embryos can be stored with the combined procedure, the limited rate of pregnancies represents a poor reproductive outcome. Therefore, this approach should be reserved for special groups with limited options.
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