Evidence map›Paper›PMID 29574570›Full record

ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2018

Identification and validation of genomic regions influencing kernel zinc and iron in maize.

Vemuri Hindu, Natalia Palacios-Rojas, Raman Babu, Willy B Suwarno, Zerka Rashid, Rayalcheruvu Usha, Gajanan R Saykhedkar, Sudha K Nair

Open access · hybridAbstract read
In one paragraph

Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
18.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 125 citations in OpenAlex.

  1. Review
  2. Review
  3. Genome-wide association study reveals genetic loci for ten trace elements in foxtail millet (Setaria italica).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024
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  15. Iron bioavailability of maize (Frontiers in plant science · 2023
    Article
  16. A systematicFrontiers in plant science · 2023
    Article
  17. Review
  18. Review
  19. Identification of Zinc Efficiency-Associated Loci (International journal of molecular sciences · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Vemuri HinduAsia Regional Maize Program, International Maize and Wheat Improvement Center (CIMMYT), ICRISAT Campus, Patancheru, Hyderabad, Telangana, 502324, India.
Natalia Palacios-RojasInternational Maize and Wheat Improvement Center (CIMMYT), Km 45 Carretera Mexico-Veracruz, 56130, Texcoco, Mexico.
Raman BabuAsia Regional Maize Program, International Maize and Wheat Improvement Center (CIMMYT), ICRISAT Campus, Patancheru, Hyderabad, Telangana, 502324, India.
Willy B SuwarnoInternational Maize and Wheat Improvement Center (CIMMYT), Km 45 Carretera Mexico-Veracruz, 56130, Texcoco, Mexico.
Zerka RashidAsia Regional Maize Program, International Maize and Wheat Improvement Center (CIMMYT), ICRISAT Campus, Patancheru, Hyderabad, Telangana, 502324, India.
Rayalcheruvu UshaSri Padmavati Mahila Visvavidyalayam (Women's University), Tirupati, Andhra Pradesh, 517502, India.
Gajanan R SaykhedkarAsia Regional Maize Program, International Maize and Wheat Improvement Center (CIMMYT), ICRISAT Campus, Patancheru, Hyderabad, Telangana, 502324, India.
Sudha K NairAsia Regional Maize Program, International Maize and Wheat Improvement Center (CIMMYT), ICRISAT Campus, Patancheru, Hyderabad, Telangana, 502324, India. sudha.nair@cgiar.org.
International Crops Research Institute for the Semi-Arid Tropics · INInternational Maize and Wheat Improvement Center · INCentro Internacional de Mejoramiento de Maíz Y Trigo · MXIPB University · IDSri Padmavati Mahila Visvavidyalayam · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

key messageGenome-wide association study (GWAS) on 923 maize lines and validation in bi-parental populations identified significant genomic regions for kernel-Zinc and-Iron in maize. Bio-fortification of maize with elevated Zinc (Zn) and Iron (Fe) holds considerable promise for alleviating under-nutrition among the world's poor. Bio-fortification through molecular breeding could be an economical strategy for developing nutritious maize, and hence in this study, we adopted GWAS to identify markers associated with high kernel-Zn and Fe in maize and subsequently validated marker-trait associations in independent bi-parental populations. For GWAS, we evaluated a diverse maize association mapping panel of 923 inbred lines across three environments and detected trait associations using high-density Single nucleotide polymorphism (SNPs) obtained through genotyping-by-sequencing. Phenotyping trials of the GWAS panel showed high heritability and moderate correlation between kernel-Zn and Fe concentrations. GWAS revealed a total of 46 SNPs (Zn-20 and Fe-26) significantly associated (P ≤ 5.03 × 10

Indexed as

Polymorphism, Single NucleotideGenetic Association StudiesGenetic MarkersGenotypeIronPhenotypePlant BreedingQuantitative Trait LociSeedsZea maysZincGenetic MarkersIronZinc

Identifiers

PMID29574570
PMCPMC6004279
OpenAlexW2789517713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.