ArticleChild abuse & neglect2018
Self-reported neglect, amygdala volume, and symptoms of anxiety in adolescent boys.
Article in Child abuse & neglect, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Interpersonal early adversity demonstrates dissimilarity from early socioeconomic disadvantage in the course of human brain development: A meta-analysis.Neuroscience and biobehavioral reviews · 2023Pooled it
- A Randomized Controlled Trial of a Parenting Intervention During Infancy Alters Amygdala-Prefrontal Circuitry in Middle Childhood.Journal of the American Academy of Child and Adolescent Psychiatry · 2024Trial
- The Longitudinal Impact of Daytime Dysfunction on Adolescent Depressive and Anxiety Symptoms: A Random Intercept Cross-Lagged Panel Study.Brain and behavior · 2026Article
- Forensic neuroimaging in childhood abduction, rape and murder case and trial outcome.Psychiatry, psychology, and law : an interdisciplinary journal of the Australian and New Zealand Association of Psychiatry, Psychology and Law · 2026Article
- Risky family environment, white matter organization, and effective parenting in expectant fathers.Development and psychopathology · 2025Article
- Child maltreatment, social capital, maternal mental health and duration of program involvement: Assessment from a community-based empowerment program in Kenya.Journal of family violence · 2023Article
- Interpersonal early adversity demonstrates dissimilarity from early socioeconomic disadvantage in the course of human brain development: A meta-analysis.bioRxiv : the preprint server for biology · 2023Article
- Left amygdala structure mediates longitudinal associations between exposure to threat and long-term psychiatric symptomatology in youth.Human brain mapping · 2022Article
- Amygdala and hippocampal subregions mediate outcomes following trauma during typical development: Evidence from high-resolution structural MRI.Neurobiology of stress · 2022Article
- Early life adversity and males: Biology, behavior, and implications for fathers' parenting.Neuroscience and biobehavioral reviews · 2022Review
- Are Anxiety and Depression Taking Sides with Knee-Pain in Osteoarthritis?Journal of clinical medicine · 2022Article
- Peer Victimization Influences Attention Processing Beyond the Effects of Childhood Maltreatment by Caregivers.Frontiers in psychology · 2022Article
- Adverse Childhood Experiences Are Associated With Adult Dream Content: A Cross-Sectional Survey.Frontiers in psychology · 2022Article
- Early Life Adversity and Neuropsychiatric Disease: Differential Outcomes and Translational Relevance of Rodent Models.Frontiers in systems neuroscience · 2022Review
- Prenatal and Childhood Adverse Events and Child Brain Morphology: A Population-Based Study.Aperture neuro · 2022Article
- Mothers' Attachment Representations and Children's Brain Structure.Frontiers in human neuroscience · 2022Article
- Anxiety among Lebanese adolescents: scale validation and correlates.BMC pediatrics · 2021Article
- Childhood maltreatment predicts subsequent anxiety symptoms among Chinese adolescents: the role of the tendency of coping styles.Translational psychiatry · 2021Article
- "She finds you abhorrent" - The impact of emotional context information on the cortical processing of neutral faces in depression.Cognitive, affective & behavioral neuroscience · 2021Article
- Effects of Early Life Stress on the Developing Basolateral Amygdala-Prefrontal Cortex Circuit: The Emerging Role of Local Inhibition and Perineuronal Nets.Frontiers in human neuroscience · 2021Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Experiences of psychosocial neglect affect the developing brain and may place individuals at increased risk for anxiety. The majority of research in this area has focused on children who have experienced severe psychosocial deprivation; it is not clear whether typical variation in neglect experienced in community samples would have the same neurobiological consequences as those documented in extreme samples. The present study examined the associations among self-reported childhood neglect, amygdala volume, and anxiety symptoms in a community sample of 138 adolescents ages 9-15 years (43% male). Linear mixed modeling yielded a three-way interaction of neglect, sex, and brain hemisphere, reflecting a significant positive association between neglect and right amygdala volume in boys. Additional analyses indicated that right amygdala volume significantly mediated the association between neglect and anxiety symptoms in boys. These findings are consistent with previous reports of larger amygdala volumes in previously institutionalized children, and with documented associations between caregiving deprivation and anxiety symptoms. The results suggest that the effects of childhood neglect on limbic structures are sex-specific and lateralized, and provide support for a neural mechanism relating childhood neglect to later difficulties in emotional functioning.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.