ReviewRegulatory toxicology and pharmacology : RTP2018
Characterizing risk assessments for the development of occupational exposure limits for engineered nanomaterials.
Review in Regulatory toxicology and pharmacology : RTP, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Oxidative stress induced by occupational exposure to nanomaterials: a systematic review.Industrial health · 2020Pooled it
- Multifunctional nanotherapeutics for tumor microenvironment modulation in solid tumor therapy.Discover nano · 2026Review
- Exposure, Cytotoxicity and Cellular Uptake of Silver (Ag) and Gold (Au) Nanoparticles in Human Bronchial Epithelial Cells During Nanoparticle Synthesis.Nanomaterials (Basel, Switzerland) · 2026Article
- Impact of physiological strain on lung epithelial cells by exposure to aerosolised quartz silica in a perfused bioreactor.Frontiers in bioengineering and biotechnology · 2026Article
- U. S. federal perspective on critical research issues in nanoEHS.Environmental science. Nano · 2023Article
- Risk Assessment of Nanomaterials Toxicity.Nanomaterials (Basel, Switzerland) · 2023Article
- Release of particulate matter from nano-enabled building materials (NEBMs) across their lifecycle: Potential occupational health and safety implications.Journal of hazardous materials · 2022Article
- NanoSafe III: A User Friendly Safety Management System for Nanomaterials in Laboratories and Small Facilities.Nanomaterials (Basel, Switzerland) · 2021Article
- Toxicological Consequences of Titanium Dioxide Nanoparticles (TiOBioNanoScience · 2021Review
- Recent Developments in the Application of Nanomaterials in Agroecosystems.Nanomaterials (Basel, Switzerland) · 2020Review
- Impaired mitochondrial function of alveolar macrophages in carbon nanotube-induced chronic pulmonary granulomatous disease.Toxicology · 2020Article
- Sustainable Use of Nanomaterials in Textiles and Their Environmental Impact.Materials (Basel, Switzerland) · 2020Review
- lapdMouse: a data archive for advancing computational models of inhaled aerosol dosimetry.Journal of applied physiology (Bethesda, Md. : 1985) · 2020Article
- Experimental Application of Semi-Quantitative Methods for the Assessment of Occupational Exposure to Hazardous Chemicals in Research Laboratories.Risk management and healthcare policy · 2020Article
- Nanoparticles: An Experimental Study of Zinc Nanoparticles Toxicity on Marine Crustaceans. General Overview on the Health Implications in Humans.Frontiers in public health · 2020Article
- An Exploratory Assessment of Applying Risk Management Practices to Engineered Nanomaterials.International journal of environmental research and public health · 2019Article
- Risk Analysis of Cellulose Nanomaterials by Inhalation: Current State of Science.Nanomaterials (Basel, Switzerland) · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The commercialization of engineered nanomaterials (ENMs) began in the early 2000's. Since then the number of commercial products and the number of workers potentially exposed to ENMs is growing, as is the need to evaluate and manage the potential health risks. Occupational exposure limits (OELs) have been developed for some of the first generation of ENMs. These OELs have been based on risk assessments that progressed from qualitative to quantitative as nanotoxicology data became available. In this paper, that progression is characterized. It traces OEL development through the qualitative approach of general groups of ENMs based primarily on read-across with other materials to quantitative risk assessments for nanoscale particles including titanium dioxide, carbon nanotubes and nanofibers, silver nanoparticles, and cellulose nanocrystals. These represent prototypic approaches to risk assessment and OEL development for ENMs. Such substance-by-substance efforts are not practical given the insufficient data for many ENMs that are currently being used or potentially entering commerce. Consequently, categorical approaches are emerging to group and rank ENMs by hazard and potential health risk. The strengths and limitations of these approaches are described, and future derivations and research needs are discussed. Critical needs in moving forward with understanding the health effects of the numerous EMNs include more standardized and accessible quantitative data on the toxicity and physicochemical properties of ENMs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.