Evidence map›Paper›PMID 29574033›Full record

ReviewNeuroImage2019

Computational neuroanatomy of baby brains: A review.

Gang Li, Li Wang, Pew-Thian Yap, Fan Wang, Zhengwang Wu, Yu Meng, Pei Dong, Jaeil Kim, Feng Shi, Islem Rekik and 2 more

Abstract readReview
In one paragraph

Review in NeuroImage, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
106citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

106 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
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  8. Article
  9. Longitudinal trajectories of brain development from infancy to school age and their relationship with literacy development.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  14. The American journal of drug and alcohol abuse · 2025
    Article
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  19. Disentangled Hybrid Transformer for Identification of Infants with Prenatal Drug Exposure.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2024
    Article
  20. Article

46 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Gang LiDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, NC 27599, USA.
Li WangDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, NC 27599, USA.
Pew-Thian YapDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, NC 27599, USA.
Fan WangDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, NC 27599, USA.
Zhengwang WuDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, NC 27599, USA.
Yu MengDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, NC 27599, USA.
Pei DongDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, NC 27599, USA.
Jaeil KimDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, NC 27599, USA; School of Computer Science and Engineering, Kyungpook National University, Daegu 41566, Republic of Korea.
Feng ShiBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Islem RekikBASIRA Lab, CVIP, Computing, School of Science and Engineering, University of Dundee, UK.
Weili LinDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, NC 27599, USA.
Dinggang ShenDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, NC 27599, USA; Department of Brain and Cognitive Engineering, Korea University, Seoul 02841, Republic of Korea. Electronic address: dgshen@med.unc.edu.

Funding

UNC/UMN Baby Connectome ProjectU01MH110274 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ELISON, JED THOMAS, GILMORE, JOHN HORACE · 2016 to 2019
$4.5M
Infant Brain Measurement and Super-Resolution Atlas ConstructionR01MH100217 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SHEN, DINGGANG · 2013 to 2016
$2.3M
Robust White Matter Morphometry with Small DatabasesR01NS093842 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2016 to 2018
$1.1M
Volume-based Analysis of 6-month Infant Brain MRI for Autism Biomarker Identification and Early DiagnosisK01MH109773 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WANG, LI · 2017 to 2020
$571k
4D Cortical Surface Analysis Tools for Study of Early Brain Development in Typical and High-risk InfantsK01MH107815 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LI, GANG · 2015 to 2018
$559k
Constructing 4-dimensional Infant Cortical Surface AtlasesR21MH108914 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LI, GANG · 2016 to 2017
$418k
NIMH NIH HHS K01 MH107815NIMH NIH HHS K01 MH109773NIMH NIH HHS R01 MH100217NIMH NIH HHS R21 MH108914NIMH NIH HHS U01 MH110274NINDS NIH HHS R01 NS093842
6 · The paper itself

Abstract

The first postnatal years are an exceptionally dynamic and critical period of structural, functional and connectivity development of the human brain. The increasing availability of non-invasive infant brain MR images provides unprecedented opportunities for accurate and reliable charting of dynamic early brain developmental trajectories in understanding normative and aberrant growth. However, infant brain MR images typically exhibit reduced tissue contrast (especially around 6 months of age), large within-tissue intensity variations, and regionally-heterogeneous, dynamic changes, in comparison with adult brain MR images. Consequently, the existing computational tools developed typically for adult brains are not suitable for infant brain MR image processing. To address these challenges, many infant-tailored computational methods have been proposed for computational neuroanatomy of infant brains. In this review paper, we provide a comprehensive review of the state-of-the-art computational methods for infant brain MRI processing and analysis, which have advanced our understanding of early postnatal brain development. We also summarize publically available infant-dedicated resources, including MRI datasets, computational tools, grand challenges, and brain atlases. Finally, we discuss the limitations in current research and suggest potential future research directions.

Indexed as

Atlases as TopicBrainComputer SimulationFemaleHumansImage Processing, Computer-AssistedInfantInfant, NewbornMagnetic Resonance ImagingMaleModels, TheoreticalNeuroanatomyNeuroimagingBrain atlasCortical surfaceInfant brainParcellationRegistrationSegmentation

Identifiers

PMID29574033
PMCPMC6150852

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.