ArticleBiological psychiatry. Cognitive neuroscience and neuroimaging2018
Hypoventilation Therapy Alleviates Panic by Repeated Induction of Dyspnea.
Article in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- From Lung to Brain: Respiration Modulates Neural and Mental Activity.Neuroscience bulletin · 2023Pooled it
- Positive affect treatment targets reward sensitivity: A randomized controlled trial.Journal of consulting and clinical psychology · 2023Trial
- Interpreting Anxiety Disorders From the Perspective of Interoceptive Computational Models.Brain and behavior · 2025Review
- Biobehavioral approach to distinguishing panic symptoms from medical illness.Frontiers in psychiatry · 2024Review
- Breathing Rhythm and Pattern and Their Influence on Emotion.Annual review of neuroscience · 2022Review
- Recent insights into respiratory modulation of brain activity offer new perspectives on cognition and emotion.Biological psychology · 2022Review
- Perceptual and Ventilatory Responses to Hypercapnia in Athletes and Sedentary Individuals.Frontiers in physiology · 2022Article
- Real-world outcomes of an innovative digital therapeutic for treatment of panic disorder and PTSD: A 1,500 patient effectiveness study.Frontiers in digital health · 2022Article
- Precision Medicine for Breath-Focused Mind-Body Therapies for Stress and Anxiety: Are We Ready Yet?Global advances in health and medicine · 2021Article
- An Anti-hyperventilation Instruction Decreases the Drop in End-tidal COApplied psychophysiology and biofeedback · 2019Article
- An Active Inference Approach to Interoceptive Psychopathology.Annual review of clinical psychology · 2019Review
- Training of paced breathing at 0.1 Hz improves CO2 homeostasis and relaxation during a paced breathing task.PloS one · 2019Article
- Defining the Rhythmogenic Elements of Mammalian Breathing.Physiology (Bethesda, Md.) · 2018Review
- Interoception and Mental Health: A Roadmap.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2018Review
- Taking Aim at Interoception's Role in Mental Health.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundPrevious research has shown that hypoventilation therapy reduces panic symptoms in part by increasing basal partial pressure of carbon dioxide (PCO
methodsA total of 35 patients with panic disorder were trained to perform exercises to raise their end-tidal PCO
resultsAs expected, within-exercise anxiety and respiratory rate decreased over time. Unexpectedly, PCO
conclusionsIn support of the interoceptive exposure model, we found that greater dyspnea during hypoventilation exercises resulted in lower panicogenic cognitions even after the effect of PCO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.