ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2018
Systemic effects of deep brain stimulation on synergic control in Parkinson's disease.
Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- A methodological scoping review on EMG processing and synergy-based results in muscle synergy studies in Parkinson's disease.Frontiers in bioengineering and biotechnology · 2024Pooled it
- Functional changes in spinal circuitry in essential tremor revealed with analysis of intramuscle synergies.Journal of neurophysiology · 2026Article
- Amplitude of Lower Limb Muscle Activation in Different Phases of the Illinois Test in Parkinson's Disease Patients: A Pilot Study.Journal of clinical medicine · 2024Article
- Muscle synergies in Parkinson's disease before and after the deep brain stimulation of the bilateral subthalamic nucleus.Scientific reports · 2023Article
- Synergic control in asymptomatic welders during multi-finger force exertion and load releasing while standing.Neurotoxicology · 2022Article
- Recent Advances in the Neural Control of Movements: Lessons for Functional Recovery.Physical therapy research · 2022Review
- One more time about motor (and non-motor) synergies.Experimental brain research · 2021Review
- Stability of Action and Kinesthetic Perception in Parkinson's Disease.Journal of human kinetics · 2021Article
- Muscle Synergies in Parkinson's Disease.Sensors (Basel, Switzerland) · 2020Review
- Synergic control of action in levodopa-naïve Parkinson's disease patients: I. Multi-finger interaction and coordination.Experimental brain research · 2020Article
- Preparation to a quick whole-body action: control with referent body orientation and multi-muscle synergies.Experimental brain research · 2019Article
- Quantitative analysis of multi-element synergy stabilizing performance: comparison of three methods with respect to their use in clinical studies.Experimental brain research · 2019Article
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8 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveWe explored effects of deep brain stimulation (DBS) in patients with Parkinson's disease (PD) on the synergic control of fingers in a multi-finger force production task and of muscles in a task involving vertical posture.
methodsThe finger task involved the four fingers of a hand producing accurate total force followed by a targeted quick force pulse. The postural task involved releasing a load from extended arms. The analysis of synergies was performed within the framework of the uncontrolled manifold hypothesis.
resultsDBS led to no significant changes in indices of stability during steady-state phases. In contrast, DBS improved indices of agility, quantified as anticipatory synergy adjustments that reduced stability of salient performance variables in preparation to their quick change. There were moderate-to-strong correlations between indices of both stability and agility measured in the multi-finger force production and multi-muscle whole-body action.
conclusionsOur results point at systemic changes in synergic control in PD. They show that DBS is effective in improving only one components of synergic control related to agility in performance being relatively ineffective for the stability component. SIGNIFICANCE: The results show systemic brain mechanisms of synergies and suggest differential effects of DBS on indices of stability and agility.
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