Evidence map›Paper›PMID 29573750›Full record

ArticleGenetics, selection, evolution : GSE2018

Genome-wide association of changes in swine feeding behaviour due to heat stress.

Amanda J Cross, Brittney N Keel, Tami M Brown-Brandl, Joseph P Cassady, Gary A Rohrer

Open access · goldAbstract read
In one paragraph

Article in Genetics, selection, evolution : GSE, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 41 citations in OpenAlex.

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  15. The Genetics of Thermoregulation in Pigs: A Review.Frontiers in veterinary science · 2021
    Review
  16. A methodology for mapping current and future heat stress risk in pigs.Animal : an international journal of animal bioscience · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Amanda J CrossDepartment of Animal Science, South Dakota State University, Brookings, SD, 57007, USA.
Brittney N KeelUSDA, ARS, U.S. Meat Animal Research Center, Clay Center, NE, 68933, USA.
Tami M Brown-BrandlUSDA, ARS, U.S. Meat Animal Research Center, Clay Center, NE, 68933, USA.
Joseph P CassadyDepartment of Animal Science, South Dakota State University, Brookings, SD, 57007, USA.
Gary A RohrerUSDA, ARS, U.S. Meat Animal Research Center, Clay Center, NE, 68933, USA. gary.rohrer@ars.usda.gov.
Roman L. Hruska U.S. Meat Animal Research Center · USSouth Dakota State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHeat stress has a negative impact on pork production, particularly during the grow-finish phase. As temperature increases, feeding behaviour changes in order for pigs to decrease heat production. The objective of this study was to identify genetic markers associated with changes in feeding behaviour due to heat stress. Feeding data were collected on 1154 grow-finish pigs using an electronic feeding system from July 2011 to March 2016. In this study, days were classified based on the maximum temperature humidity index (THI) during the day as "Normal" (< 23.33 °C), "Alert" (23.33 °C ≤ × < 26.11 °C), "Danger" (26.11 °C ≤ × < 28.88 °C), and "Emergency" (≥ 28.88 °C). Six hundred and eighty-one pigs that experienced more than one THI category were genotyped using a variety of SNP platforms, with final genotypes imputed to approximately 60,000 markers.

resultsA genome-wide association study (GWAS) for change in feeding behaviour between each pair of THI categories (six pairs) was conducted. Estimates of heritability for differences in feeding activity between each of the THI categories were low (0.02 ± 0.03) to moderate (0.21 ± 0.04). Sixty-six associations which explained more than 1% of the genomic variation for a trait were detected across the six GWAS, with the smallest number of associations detected in comparisons with Emergency THI. Gene ontology enrichment analysis showed that biological processes related to immune response and function were over-represented among the genes located in these regions.

conclusionsGenetic differences exist for changes in feeding behaviour induced by elevated ambient temperatures in grow-finish pigs. Selection for heat-tolerant grow-finish pigs should improve production efficiency during warm months in commercial production. Genetic variation in heat shock, stress response and immune function genes may be responsible for the observed differences in performance during heat stress events.

Indexed as

Feeding BehaviorPolymorphism, Single NucleotideAnimalsBayes TheoremGenetic Predisposition to DiseaseGenome-Wide Association StudyGenotypeGenotyping TechniquesHeat Stress DisordersHumidityQuantitative Trait, HeritableSwineSwine Diseases

Identifiers

PMID29573750
PMCPMC5866911
OpenAlexW2799944893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.