Evidence map›Paper›PMID 29573659›Full record

Trial reportPsychiatry research2018

Evaluating the genetic susceptibility to peer reported bullying behaviors.

Rashelle J Musci, Amie F Bettencourt, Danielle Sisto, Brion Maher, George Uhl, Nicholas Ialongo, Catherine P Bradshaw

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Psychiatry research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Rashelle J MusciDepartment of Mental Health, Johns Hopkins University, Bloomberg School of Public Health, 624 North Broadway, Baltimore, MD 21205, USA. Electronic address: rmusci1@jhu.edu.
Amie F BettencourtDepartment of Mental Health, Johns Hopkins University, Bloomberg School of Public Health, 624 North Broadway, Baltimore, MD 21205, USA; Department of Psychiatry and Behavioral Sciences, Division of Child and Adolescent Psychiatry, Johns Hopkins School of Medicine, 550 North Broadway, Baltimore, MD 21205, USA.
Danielle SistoDepartment of Mental Health, Johns Hopkins University, Bloomberg School of Public Health, 624 North Broadway, Baltimore, MD 21205, USA.
Brion MaherDepartment of Mental Health, Johns Hopkins University, Bloomberg School of Public Health, 624 North Broadway, Baltimore, MD 21205, USA.
George UhlResearch Service, New Mexico VA Healthcare System, Departments of Neurology, Neuroscience and Molecular Genetics and Microbiology, University of New Mexico, Departments of Neurology, Neuroscience and Mental Health, Johns Hopkins Medical Institutions.
Nicholas IalongoDepartment of Mental Health, Johns Hopkins University, Bloomberg School of Public Health, 624 North Broadway, Baltimore, MD 21205, USA.
Catherine P BradshawDepartment of Mental Health, Johns Hopkins University, Bloomberg School of Public Health, 624 North Broadway, Baltimore, MD 21205, USA; Curry School of Education, University of Virginia, PO Box 400270, Charlottesille, VA 22904, USA.
Johns Hopkins University · USUniversity of New Mexico · USUniversity of Virginia · US

Funding

PERIODIC FOLLOW UP OF TWO UNIVERSAL PREVENTIVE TRIALSR01MH057005 · NIMH · JOHNS HOPKINS UNIVERSITY · PI IALONGO, NICHOLAS S · 1998 to 2007
$4.2M
Development & Malleability from Childhood to AdulthoodR01DA044184 · NIDA · JOHNS HOPKINS UNIVERSITY · PI IALONGO, NICHOLAS S · 2018 to 2022
$3.9M
Development &Malleability from Childhood to AdulthoodR37DA011796 · NIDA · JOHNS HOPKINS UNIVERSITY · PI IALONGO, NICHOLAS S · 2005 to 2013
$3.6M
PREVENTIVE RESEARCH TRAINING IN MENTAL HEALTHT32MH018834 · NIMH · JOHNS HOPKINS UNIVERSITY · PI IALONGO, NICHOLAS S · 1988 to 2011
$2.3M
FOLLOWUP OF TWO UNIVERSAL PREVENTIVE INTERVENTIONSR01DA011796 · NIDA · JOHNS HOPKINS UNIVERSITY · PI IALONGO, NICHOLAS S · 1999 to 2004
$2.0M
Genes, Environment and Drug Use in Three Baltimore CohortsR01DA036525 · NIDA · JOHNS HOPKINS UNIVERSITY · PI MAHER, BRION S · 2015 to 2017
$727k
NIDA NIH HHS R01 DA011796NIDA NIH HHS R01 DA036525NIDA NIH HHS R01 DA044184NIDA NIH HHS R37 DA011796NIMH NIH HHS R01 MH057005
6 · The paper itself

Abstract

Bullying is a significant public health concern with lasting impacts on youth. Although environmental risk factors for bullying have been well-characterized, genetic influences on bullying are not well understood. This study explored the role of genetics on early childhood bullying behavior. Participants were 561 children who participated in a longitudinal randomized control trial of a preventive intervention beginning in first grade who were present for the first grade peer nominations used to measure early childhood bullying and who provided genetic data during the age 19-21 year follow-up in the form of blood or saliva. Measures included a polygenic risk score (PRS) derived from a conduct disorder genome wide association study. Latent profile analysis identified three profiles of bullying behaviors during early childhood. Results suggest that the PRS was significantly associated with class membership, with individuals in the moderate bully-victim profile having the highest levels of the PRS and those in the high bully-victim profile having the lowest levels. This line of research has important implications for understanding genetic vulnerability to bullying in early childhood.

Indexed as

BullyingPeer GroupAdolescentChildChild, PreschoolConduct DisorderCrime VictimsFemaleGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansLongitudinal StudiesMale

Identifiers

PMID29573659
PMCPMC6085882
OpenAlexW2791680403

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.