Evidence map›Paper›PMID 29573649›Full record

ArticleDrug and alcohol dependence2018

Perceptions and practices addressing diversion among US buprenorphine prescribers.

Lewei Allison Lin, Michelle R Lofwall, Sharon L Walsh, Adam J Gordon, Hannah K Knudsen

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lewei Allison LinUniversity of Michigan, Department of Psychiatry, 2800 Plymouth Road, Ann Arbor, MI 48109, USA; VA Center for Clinical Management Research (CCMR), Department of Veterans Affairs Healthcare System, 2800 Plymouth Rd., Ann Arbor, MI 48109, USA. Electronic address: leweil@med.umich.edu.
Michelle R LofwallUniversity of Kentucky, Department of Behavioral Science and Center on Drug and Alcohol Research, 845 Angliana Avenue, Lexington, KY 40508, USA.
Sharon L WalshUniversity of Kentucky, Department of Behavioral Science and Center on Drug and Alcohol Research, 845 Angliana Avenue, Lexington, KY 40508, USA.
Adam J GordonUniversity of Utah, Division of Epidemiology, Department of Medicine, 295 Chipeta Way, Salt Lake City UT 84132, USA; VA Salt Lake City Health Care System, Informatics, Decision-Enhancement and Analytic Sciences Center (IDEAS 2.0) and Section of Addiction Medicine, 500 Foothill Drive, Salt Lake City, UT 84148, USA.
Hannah K KnudsenUniversity of Kentucky, Department of Behavioral Science and Center on Drug and Alcohol Research, 845 Angliana Avenue, Lexington, KY 40508, USA.
University of Kentucky · USUniversity of Michigan–Ann Arbor · USVA Salt Lake City Healthcare System · US

Funding

Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2M
Kentucky Center for Clinical and Translational ScienceUL1TR000117 · NCATS · UNIVERSITY OF KENTUCKY · PI KERN, PHILIP A · 2012 to 2015
$13.3M
Buprenorphine Treatment and Health Reform: Availability, Utilization, and QualityR33DA035641 · NIDA · UNIVERSITY OF KENTUCKY · PI KNUDSEN, HANNAH · 2014 to 2017
$2.0M
NCATS NIH HHS UL1 TR000117NCATS NIH HHS UL1 TR001998NIDA NIH HHS R33 DA035641
6 · The paper itself

Abstract

backgroundWhile there has been a dramatic increase in prescribing of buprenorphine for the treatment of opioid use disorder in the US, little is known about prescribers' attitudes and practices regarding buprenorphine diversion and how they relate to prescriber characteristics.

methodsA national random sample of buprenorphine prescribers (N = 1174) completed surveys from July 2014 to January 2017. Analyses examined relationships between prescriber and practice characteristics and prescriber perceptions and approaches regarding diversion.

resultsAmong this sample of buprenorphine prescribers, 79.0% (N = 898) reported assessing all patients for risk of buprenorphine diversion and misuse. A third of prescribers described diversion as a significant or very significant concern in their community. The majority of prescribers reported seeing patients on average at least every other week during the first 60 days of treatment, and the majority reported testing urine for buprenorphine to assess for diversion. Perceptions of diversion being a greater problem in their community (AOR 1.212, 95% CI 1.073-1.369) and use of medication counts (AOR 1.006, 95% CI 1.003-1.009) were associated with increased likelihood of terminating patients when diversion was suspected, while having expertise in addiction (AOR 0.526, 95% CI 0.406-0.682) or psychiatry (AOR 0.714, 95% CI 0.558-0.914) were associated with decreased odds of terminating treatment for suspected diversion.

conclusionsBuprenorphine prescribers report diversion is an important issue, and most prescribers report that they assess patients for diversion, though specific practices differ based on prescriber and practice characteristics.

Indexed as

BuprenorphineNarcotic AntagonistsAdultDrug PrescriptionsFemaleHealth Knowledge, Attitudes, PracticeHealth PersonnelHumansMaleMiddle AgedOpioid-Related DisordersPrescription Drug DiversionUnited StatesBuprenorphineNarcotic AntagonistsBuprenorphineDiversionOpioid use disorderProvidersTreatment

Identifiers

PMID29573649
PMCPMC5911230
OpenAlexW2792993837

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.