Evidence map›Paper›PMID 29573256›Full record

ReviewMicrobiology spectrum2018

Global Regulation by CsrA and Its RNA Antagonists.

Tony Romeo, Paul Babitzke

Open access · greenAbstract readReview
In one paragraph

Review in Microbiology spectrum, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed
15.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 168 citations in OpenAlex.

  1. Virulence · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Sugar Import SuppressesbioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Unexpected Richness of the Bacterial Small RNA World.Journal of molecular biology · 2025
    Review
  11. Article
  12. Article
  13. Control ofmBio · 2025
    Article
  14. Article
  15. Article
  16. Review
  17. mBio · 2024
    Article
  18. Article
  19. Article
  20. Article

44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Tony RomeoDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL 32611.
Paul BabitzkeDepartment of Biochemistry and Molecular Biology.
Pennsylvania State University · USUniversity of Florida · US

Funding

Mechanism of CsrA-mediated global regulationR01GM059969 · NIGMS · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI BABITZKE, PAUL L, ROMEO, TONY · 1999 to 2021
$7.6M
Coordination of metabolism and virulence during infectionR01AI097116 · NIAID · OHIO STATE UNIVERSITY · PI AHMER, BRIAN M, ROMEO, TONY · 2012 to 2016
$2.0M
NIAID NIH HHS R01 AI097116NIGMS NIH HHS R01 GM059969
6 · The paper itself

Abstract

The sequence-specific RNA binding protein CsrA is employed by diverse bacteria in the posttranscriptional regulation of gene expression. Its binding interactions with RNA have been documented at atomic resolution and shown to alter RNA secondary structure, RNA stability, translation, and/or Rho-mediated transcription termination through a growing number of molecular mechanisms. In

Indexed as

Bacterial ProteinsBinding SitesEscherichia coliEscherichia coli ProteinsGammaproteobacteriaGene Expression Regulation, BacterialMolecular StructureProtein BindingRepressor ProteinsRNA, BacterialRNA-Binding ProteinsRNA, MessengerRNA StabilityTranscription FactorsType III Secretion SystemsBacterial ProteinsCsrA protein, E coliEscherichia coli ProteinsRepressor ProteinsRNA, BacterialRNA-Binding ProteinsRNA, MessengerTranscription FactorsType III Secretion Systems

Identifiers

PMID29573256
PMCPMC5868435
OpenAlexW2793373052

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.