ArticleMicrobiologyOpen2018
Regulatory role of the RstB-RstA system in adhesion, biofilm production, motility, and hemolysis.
Article in MicrobiologyOpen, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 35 citations in OpenAlex.
- RstAB activates type 1 fimbriae to promote uropathogeniciScience · 2026Article
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- Regulation of type 3 fimbria expression by RstA affects biofilm formation and virulence inMicrobiology spectrum · 2025Article
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- Screening and functional characterization of isocitrate lyase AceA in the biofilm formation ofApplied and environmental microbiology · 2024Article
- Uncovering the determinants of model Escherichia coli strain C600 susceptibility and resistance to lytic T4-like and T7-like phage.Virus research · 2023Article
- Vibrio cholerae senses human enteric α-defensin 5 through a CarSR two-component system to promote bacterial pathogenicity.Communications biology · 2022Article
- A comparative whole-genome approach identifies bacterial traits for marine microbial interactions.Communications biology · 2022Article
- Potential dsRNAs can be delivered to aquatic for defense pathogens.Frontiers in bioengineering and biotechnology · 2022Review
- Co-Lateral Effect of Octenidine, Chlorhexidine and Colistin Selective Pressures on Four Enterobacterial Species: A Comparative Genomic Analysis.Antibiotics (Basel, Switzerland) · 2021Article
- RNA-seq analysis of antibacterial mechanism ofPeerJ · 2021Article
- Motility of Vibrio spp.: regulation and controlling strategies.Applied microbiology and biotechnology · 2020Review
- Engineering regulatory networks for complex phenotypes in E. coli.Nature communications · 2020Article
- First Succinylome Profiling ofFrontiers in cellular and infection microbiology · 2020Article
- Genome Insights of the Plant-Growth Promoting BacteriumFrontiers in microbiology · 2020Article
- The regulation of oxidative phosphorylation pathway on Vibrio alginolyticus adhesion under adversities.MicrobiologyOpen · 2019Article
- RstA, a two-component response regulator, plays important roles in multiple virulence-associated processes in enterohemorrhagicGut pathogens · 2019Article
- The RstAB System Impacts Virulence, Motility, Cell Morphology, Penicillin Tolerance and Production of Type II Secretion System-Dependent Factors in the Fish and Human PathogenFrontiers in microbiology · 2019Article
- Regulatory role of the RstB-RstA system in adhesion, biofilm production, motility, and hemolysis.MicrobiologyOpen · 2018Article
- Cytotoxin- and Chemotaxis-Genes Cooperate to Promote Adhesion ofFrontiers in microbiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For infection, initial invasion of the host is of great importance, with adhesion playing a critical role. We previously demonstrated rstA and rstB are remarkably downregulated in Vibrio alginolyticus cultured under heavy metal and acidic stresses, with impaired adhesion, suggesting that rstA and rstB might be involved in adhesion regulation. The present study showed that rstA and rstB silencing resulted in impaired adhesion, biofilm production, motility, hemolysis, and virulence. Meanwhile, changes of temperature, starvation, and pH remarkably affected rstA and rstB expression. These findings indicated that (1) rstA and rstB are critical regulators of adhesion in V. alginolyticus; (2) rstA and rstB have remarkable effects on biofilm production, motility, hemolysis, and virulence in V. alginolyticus; (3) rstA and rstB modulate adhesion in response to environmental changes of temperature, pH, and starvation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.