ArticleJournal of veterinary internal medicine2018
Detection and seroprevalence of morbillivirus and other paramyxoviruses in geriatric cats with and without evidence of azotemic chronic kidney disease.
Article in Journal of veterinary internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 39 citations in OpenAlex.
- Pathological alteration and caspase-dependent activity of feline kidneys in natural infection of feline morbillivirus.BMC veterinary research · 2025Article
- Detection of Antibodies against Feline Morbillivirus by Recombinant Matrix Enzyme-Linked Immunosorbent Assay.Viruses · 2024Article
- Detection of feline morbillivirus in cats with symptoms of acute febrile infection.Veterinary research communications · 2024Article
- In Vitro Modeling of Feline Morbillivirus Infections Using Primary Feline Kidney Cells.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Feline Morbillivirus: Clinical Relevance of a Widespread Endemic Viral Infection of Cats.Viruses · 2023Review
- Genetic Diversity and Evolution of Viruses InfectingViruses · 2023Review
- FeMV is a cathepsin-dependent unique morbillivirus infecting the kidneys of domestic cats.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- In Vitro Growth, Receptor Usage and Pathogenesis of Feline Morbillivirus in the Natural Host.Viruses · 2022Article
- Feline Morbillivirus in Southern Italy: Epidemiology, Clinico-Pathological Features and Phylogenetic Analysis in Cats.Viruses · 2021Article
- Molecular characterization of Feline paramyxovirus and Feline morbillivirus in cats from Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021Article
- Feline morbillivirus in northwestern Italy: first detection of genotype 1-B.Journal of feline medicine and surgery · 2021Article
- Review
- Article
- High seroprevalence of feline morbilliviruses in free-roaming domestic cats in Chile.Archives of virology · 2021Article
- Article
- Molecular epidemiology and genome analysis of feline morbillivirus in household and shelter cats in Thailand.BMC veterinary research · 2020Article
- Early Renal Involvement in Cats with Natural Feline Morbillivirus Infection.Animals : an open access journal from MDPI · 2020Article
- Feline Morbillivirus, a New Paramyxovirus Possibly Associated with Feline Kidney Disease.Viruses · 2020Review
- Epidemiology, pathological aspects and genome heterogeneity of feline morbillivirus in Italy.Veterinary microbiology · 2020Article
- Molecular detection and characterisation of feline morbillivirus in domestic cats in Malaysia.Veterinary microbiology · 2019Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFeline morbillivirus (FeMV) is associated with the presence of tubulo-interstitial nephritis (TIN) in cats, however the seroprevalence of FeMV in the UK and the association between the presence of FeMV and renal azotemia is unknown HYPOTHESIS/
objectivesTo identify whether paramyxoviruses are present in urine samples of geriatric cats and to develop an assay to assess FeMV seroprevalence. To investigate the relationship between both urinary paramyxovirus (including FeMV) excretion and FeMV seroprevalence and azotemic chronic kidney disease (CKD). ANIMALS: Seventy-nine cats (40 for FeMV detection; 72 for seroprevalence).
methodsRetrospective cross-sectional, case control study. Viral RNA was extracted from urine for RT-PCR. PCR products were sequenced for virus identification and comparison. The FeMV N protein gene was cloned and partially purified for use as an antigen to screen cat sera for anti-FeMV antibodies by Western Blot.
resultsFeline morbillivirus RNA from five distinct morbilliviruses were identified. Detection was not significantly different between azotemic CKD (1/16) and nonazotemic groups (4/24; P = .36). Three distinct, non-FeMV paramyxoviruses were present in the nonazotemic group but their absence from the azotemic group was not statistically significant (P = .15). 6/14 (43%) azotemic cats and 40/55 (73%) nonazotemic cats were seropositive (P = .06). CONCLUSIONS AND CLINICAL IMPORTANCE: Feline morbillivirus was detected in cats in the UK for the First time. However, there was no association between virus prevalence or seropositivity and azotemic CKD. These data do not support the hypothesis that FeMV infection is associated with the development of azotemic CKD in cats in the UK.
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