ArticleJournal of veterinary internal medicine2018
Prognostic value of echocardiographic indices of left atrial morphology and function in dogs with myxomatous mitral valve disease.
Article in Journal of veterinary internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Prognostic interaction between clinical stage and left atrial remodeling in dogs with myxomatous mitral valve disease.The veterinary quarterly · 2026Article
- Prognostic relevance of short-term changes in body weight, renal indices, and echocardiographic variables after intravenous diuretic therapy in dogs with myxomatous mitral valve disease hospitalized for pulmonary edema.The veterinary quarterly · 2026Article
- Mitral annular plane systolic excursion to left atrial volume ratio as a novel index to assess ventricular filling pressure in dogs with myxomatous mitral valve disease.Veterinary research communications · 2026Article
- Short-term effects of pimobendan in dogs with preclinical myxomatous mitral valve disease.Frontiers in veterinary science · 2026Article
- Impact of administering cardiac medication to small-breed dogs with preclinical myxomatous mitral valve disease on survival after congestive heart failure onset.The veterinary quarterly · 2025Article
- Echocardiographic Changes in Dogs with Stage B2 Myxomatous Mitral Valve Disease Treated with Pimobendan Monotherapy.Veterinary sciences · 2024Article
- Alteration of clinical parameters before mortality and prognostic outcomes of pulmonary hypertension in dogs with myxomatous mitral valve disease.Open veterinary journal · 2024Article
- Myxomatous Mitral Valve Disease in Large Breed Dogs: Survival Characteristics and Prognostic Variables.Veterinary sciences · 2024Article
- Risk Factors for Atrial Fibrillation in the Dog: A Systematic Review.Veterinary sciences · 2024Review
- Predictive value of left atrial volumes assessed using real-time three-dimensional echocardiography for pulmonary hypertension in dogs with myxomatous mitral valve disease.Frontiers in veterinary science · 2024Article
- Article
- Risk factors for atrial fibrillation in dogs with dilated cardiomyopathy.Frontiers in veterinary science · 2023Article
- Prevalence and prognostic role of L wave and selected clinical and echocardiographic variables in dogs with atrial fibrillation.Journal of veterinary internal medicine · 2023Article
- Prevalence of Reticulocytosis in the Absence of Anemia in Dogs with Cardiogenic Pulmonary Edema Due to Myxomatous Mitral Valve Disease: A Retrospective Study.Veterinary sciences · 2022Article
- Performance of Different Echocardiographic Measurements of Left Atrial Size in Dogs by Observers with Different Levels of Experience.Animals : an open access journal from MDPI · 2022Article
- Lung Ultrasound for Imaging of B-Lines in Dogs and Cats-A Prospective Study Investigating Agreement between Three Types of Transducers and the Accuracy in Diagnosing Cardiogenic Pulmonary Edema, Pneumonia and Lung Neoplasia.Animals : an open access journal from MDPI · 2021Article
- Role of Two-Dimensional Speckle-Tracking Echocardiography in Early Detection of Left Ventricular Dysfunction in Dogs.Animals : an open access journal from MDPI · 2021Review
- Red Cell Distribution Width Has a Negative Prognostic Role in Dogs with Myxomatous Mitral Valve Disease.Animals : an open access journal from MDPI · 2021Article
- Utility of point-of-care lung ultrasound for monitoring cardiogenic pulmonary edema in dogs.Journal of veterinary internal medicine · 2021Article
- Diagnostic Imaging of Cardiovascular Disease in Small Animals.Animals : an open access journal from MDPI · 2020Article
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Authors and funding
7 authors.
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Abstract
backgroundThe prognostic relevance of left atrial (LA) morphological and functional variables, including those derived from speckle tracking echocardiography (STE), has been little investigated in veterinary medicine.
objectivesTo assess the prognostic value of several echocardiographic variables, with a focus on LA morphological and functional variables in dogs with myxomatous mitral valve disease (MMVD). ANIMALS: One-hundred and fifteen dogs of different breeds with MMVD.
methodsProspective cohort study. Conventional morphologic and echo-Doppler variables, LA areas and volumes, and STE-based LA strain analysis were performed in all dogs. A survival analysis was performed to test for the best echocardiographic predictors of cardiac-related death.
resultsMost of the tested variables, including all LA STE-derived variables were univariate predictors of cardiac death in Cox proportional hazard analysis. Because of strong correlation between many variables, only left atrium to aorta ratio (LA/Ao > 1.7), mitral valve E wave velocity (MV E vel > 1.3 m/s), LA maximal volume (LAVmax > 3.53 mL/kg), peak atrial longitudinal strain (PALS < 30%), and contraction strain index (CSI per 1% increase) were entered in the univariate analysis, and all were predictors of cardiac death. However, only the MV E vel (hazard ratio [HR], 4.45; confidence interval [CI], 1.76-11.24; P < .001) and LAVmax (HR, 2.32; CI, 1.10-4.89; P = .024) remained statistically significant in the multivariable analysis. CONCLUSIONS AND CLINICAL IMPORTANCE: The assessment of LA dimension and function provides useful prognostic information in dogs with MMVD. Considering all the LA variables, LAVmax appears the strongest predictor of cardiac death, being superior to LA/Ao and STE-derived variables.
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