Evidence map›Paper›PMID 29572837›Full record

ArticleThe Journal of physiology2018

Cholecystokinin selectively activates short axon cells to enhance inhibition of olfactory bulb output neurons.

Xiang Liu, Shaolin Liu

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. CCKergic Tufted Cells Differentially Drive Two Anatomically Segregated Inhibitory Circuits in the Mouse Olfactory Bulb.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  7. Review
  8. Intracerebroventricular Administration of Neural Stem Cells after Cardiac Arrest.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2019
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Xiang LiuDepartment of Anatomy & Neurobiology, Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID 0000-0002-9367-6549
Shaolin LiuDepartment of Anatomy & Neurobiology, Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID 0000-0003-3351-8642
University of Maryland, Baltimore · US

Funding

Mechanisms underlying APOE-4 effects on olfactory bulb circuitsR01DC014447 · NIDCD · UNIVERSITY OF MARYLAND BALTIMORE · PI LIU, SHAOLIN · 2016 to 2020
$1.6M
NIDCD NIH HHS R01 DC014447
6 · The paper itself

Abstract

key pointsCholecystokinin (CCK) via CCK-B receptors significantly enhances the GABA ABSTRACT: Neuropeptides such as cholecystokinin (CCK) are important for many brain functions, including sensory processing. CCK is predominantly present in a subpopulation of excitatory neurons and activation of CCK receptors is implicated in olfactory signal processing in the olfactory bulb (OB). However, the cellular and circuit mechanisms underlying the actions of CCK in the OB remain elusive. In the present study, we characterized the effects of CCK on synaptic inhibition of the principal OB output neurons mitral/tufted cells (MTCs) followed by mechanistic analyses at both circuit and cellular levels. First, we found that CCK via CCK-B receptors enhances the GABA

Indexed as

Action PotentialsAnimalsAxonsCholecystokininFemaleGABAergic NeuronsMaleMiceMice, Inbred C57BLMice, Inbred DBANeural InhibitionOlfactory BulbReceptor, Cholecystokinin BReceptors, GABA-ASynaptic TransmissionCholecystokininReceptor, Cholecystokinin BReceptors, GABA-Acholecystokinininhibitory synaptic transmissionneuromodulationolfactory bulb

Identifiers

PMID29572837
PMCPMC5983204
OpenAlexW2806577099

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.