Evidence map›Paper›PMID 29572809›Full record

ArticleEuropean journal of immunology2018

PLZF-expressing CD4 T cells show the characteristics of terminally differentiated effector memory CD4 T cells in humans.

Yeung-Hyen Kim, Lingqiao Zhu, Kalyani Pyaram, Cesar Lopez, Richard G Ohye, J Victor Garcia, Glenn E Green, Cheong-Hee Chang

Open access · bronzeAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. PLZF-expressing CD4Cell communication and signaling : CCS · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Yeung-Hyen KimDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, USA.
Lingqiao ZhuDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, USA.
Kalyani PyaramDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, USA.
Cesar LopezDivision of Infectious, Disease, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC, USA.
Richard G OhyeDepartment of Cardiac Surgery, University of Michigan Medical School, Ann Arbor, MI, USA.
J Victor GarciaDivision of Infectious, Disease, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC, USA.
Glenn E GreenDepartment of Otolaryngology-Head and Neck Surgery, University of Michigan Medical School, Ann Arbor, MI, USA.
Cheong-Hee ChangDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, USA.
University of Michigan–Ann Arbor · USUniversity of North Carolina at Chapel Hill · USViva Biotech (China) · CN

Funding

XenograftP30CA046592 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Scott Michael Schuetze · 1988 to 2026
$178.2M
Using NK Cells to eliminate the latent HIV reservoirU19AI096113 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PLANELLES, VICENTE · 2011 to 2015
$39.5M
Vaginal/Rectal HIV Transmission ModelR01AI073146 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI GARCIA-MARTINEZ, J. VICTOR · 2007 to 2016
$4.8M
Plug & Purge: In Vivo Targeting of Active HIV Reservoirs That Persist Despite ARTR01AI111899 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GARCIA-MARTINEZ, J. VICTOR · 2014 to 2018
$2.5M
Immune regulation by thymocyte-selected CD4 T cellsR01AI073677 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHANG, CHEONG-HEE · 2009 to 2013
$1.6M
NCI NIH HHS P30 CA046592NIAID NIH HHS R01 AI073146NIAID NIH HHS R01 AI073677NIAID NIH HHS R01 AI111899NIAID NIH HHS U19 AI096113
6 · The paper itself

Abstract

We show the presence of lymphoid tissue-resident PLZF

Indexed as

GenotypeCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell DifferentiationCells, CulturedGranzymesHLA-DR AntigensHumansImmunity, CellularImmunologic MemoryLymphoid TissuePerforinPromyelocytic Leukemia Zinc Finger ProteinT-Lymphocyte SubsetsGranzymesHLA-DR AntigensPerforinPromyelocytic Leukemia Zinc Finger ProteinCD4 T cellsHuman lymphoid tissuePLZFTemra cells

Identifiers

PMID29572809
PMCPMC6748641
OpenAlexW2789382955

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.