Evidence map›Paper›PMID 29572573›Full record

ArticleDysphagia2018

Longitudinal Evaluation of Swallowing with Videofluoroscopy in Patients with Locally Advanced Head and Neck Cancer After Chemoradiation.

Ekaterini Xinou, Ioannis Chryssogonidis, Anna Kalogera-Fountzila, Dimitra Panagiotopoulou-Mpoukla, Athanasia Printza

Abstract read
PubMed Publisher
In one paragraph

Article in Dysphagia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
5.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Deglutition disorders as a consequence of head and neck cancer therapies: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
    Pooled it
  3. Pooled it
  4. Trial
  5. Trial
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  8. Review
  9. Article
  10. Article
  11. Comparison of Submental Surface Electromyography during Dry Swallow between Irradiated Head and Neck Cancer Survivors and Normal Individuals.Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP) · 2024
    Article
  12. Screening oropharyngeal dysphagia in patients with head and neck cancer in a radiation oncology department.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2023
    Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ekaterini XinouDepartment of Radiology, Theagenio Cancer Hospital, Al. Simeonidi 2, 54007, Thessaloníki, Greece. katxinou@otenet.gr.ORCID 0000-0003-1573-8123
Ioannis ChryssogonidisDepartment of Radiology, Aristotle University of Thessaloniki School of Medicine, AHEPA University Hospital, St. Kiriakidi 1, 54636, Thessaloníki, Greece.
Anna Kalogera-FountzilaDepartment of Radiology, Aristotle University of Thessaloniki School of Medicine, AHEPA University Hospital, St. Kiriakidi 1, 54636, Thessaloníki, Greece.
Dimitra Panagiotopoulou-MpouklaDepartment of Radiology, Theagenio Cancer Hospital, Al. Simeonidi 2, 54007, Thessaloníki, Greece.
Athanasia PrintzaFirst Department of Oto-rhino-laryngology, Aristotle University of Thessaloniki School of Medicine, AHEPA University Hospital, St. Kiriakidi 1, 54636, Thessaloníki, Greece.
Aristotle University of Thessaloniki · GRTheageneio General Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the prevalence, severity, and pattern of evolution of swallowing impairments encountered in head and neck cancer (HNC) patients before and after chemoradiation (CRT) with videofluoroscopy of swallowing study (VFSS), using the modified barium swallow impairment profile (MBSImP) protocol and scoring system, and to determine the appropriate time points in which these patients should undergo VFSS post-CRT. A prospective cohort of 69 patients with locally advanced HNC underwent VFSS with the MBSImP protocol at 5 evaluation points: pre-CRT, and 1, 3, 6, and 12 months post-CRT. VFSS was scored with MBSImP, penetration-aspiration scale (PAS), and swallowing performance status (SPS) scale. Statistical analysis was performed only for the 12-month disease-free subset of patients. MBSImP, PAS, and SPS scale scores reached their peak at 3 months post-CRT and improved at 6-12 months, but without returning at pre-treatment levels. Base of tongue retraction, initiation of pharyngeal swallow, epiglottic movement, laryngeal vestibule closure, and laryngeal elevation were the most frequently observed impaired MBSImP components. Epiglottic movement significantly improved (p = 0.009) and laryngeal vestibule closure significantly deteriorated (p = 0.042) over time (Friedman test). Severe swallowing deficits and high aspiration rates are observed in HNC patients pre-CRT, which further deteriorate post-CRT, peak at 3 months, and despite slight improvement, persist over time. We suggest that these patients, regardless of the presence of subjective dysphagia, should undergo VFSS both before and 3 months post-CRT, and also if possible, 1 month post-CRT, in order to facilitate implementation of early swallowing rehabilitation.

Indexed as

AdultAgedChemoradiotherapyCohort StudiesDeglutitionDeglutition DisordersFemaleFluoroscopyHead and Neck NeoplasmsHumansMaleMiddle AgedProspective StudiesChemoradiotherapyDeglutitionDeglutition disordersDysphagiaHead and neck cancerMBSImPModified barium swallowVideofluoroscopy of swallowing

Identifiers

PMID29572573
OpenAlexW2790962559

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.