ArticleInternational journal of legal medicine2019
A 2-year follow-up MRI study for the evaluation of an age estimation method based on knee bone development.
Article in International journal of legal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Magnetic resonance imaging of the knee for chronological age estimation-a systematic review.European radiology · 2023Pooled it
- Magnetic resonance imaging for forensic age estimation in living children and young adults: a systematic review.Pediatric radiology · 2020Pooled it
- Combined Letrozole and Growth Hormone Therapy in Late-Pubertal Males with Advanced Bone Age and Open Knee Physes.Children (Basel, Switzerland) · 2026Article
- Final height prediction of girls at menarche: a combined model using left hand and wrist bone age, knee radiomic scores, and clinical characteristics.World journal of pediatrics : WJP · 2026Article
- Forensic age estimation using Vieth classification in adolescents of northern China based on the knee MRI.International journal of legal medicine · 2025Article
- Magnetic resonance imaging of knees: a novel approach to predict recombinant human growth hormone therapy response in short-stature children in late puberty.World journal of pediatrics : WJP · 2024Article
- Forensic age estimation of the knee by post-mortem DR, CT, and MR imaging: a comparative study.International journal of legal medicine · 2024Article
- Forensic age prediction and age classification for critical age thresholds via 3.0T magnetic resonance imaging of the knee in the Chinese Han population.International journal of legal medicine · 2022Article
- Forensic age estimation based on magnetic resonance imaging of the proximal humeral epiphysis in Chinese living individuals.International journal of legal medicine · 2021Article
- Automated age estimation of young individuals based on 3D knee MRI using deep learning.International journal of legal medicine · 2021Article
- The relevance of body mass index in forensic age assessment of living individuals: an age-adjusted linear regression analysis using multivariable fractional polynomials.International journal of legal medicine · 2020Article
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Authors and funding
6 authors at 2 institutions in 1 country.
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Abstract
Age estimation is an actual topic in the area of forensic medicine with a special focus on the age limits of 16 and 18 years. Current research on this topic relies on retrospective data of inhomogeneous populations relating to sex, age range, and socioeconomic status. In this work, we present a 2-year follow-up study for the evaluation of an age estimation method on a prospective magnetic resonance imaging (MRI) knee data collective of a homogeneous population. The study includes 40 male subjects from northern Germany aged 14 to 21 years. Three MRI examinations were evenly acquired within 2 years for each subject. As a first evaluation, a three-stage system was used to assess the ossification status of the knee (I:"open", II:"partially ossified", III:"fully ossified"). Three raters assessed the growth plate of the distal femur, proximal tibia, and proximal fibula based on central 2D slices. A good inter-rater agreement was attained (κ = 0.84). All subjects younger than 18 years were rated as stage I and had a cumulative knee score (SKJ) ≤ 5. Based on the follow-up datasets, new parameters quantifying the intra-individual ossification process were calculated. The results of this follow-up analysis show a different start, end, and speed of each growth plate's maturation as well as an ossification peak for individuals at the age of 16. The generated MRI database provides new insights into the ossification process over time and serves as a basis for further evaluations of age estimation methods.
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