Evidence map›Paper›PMID 29572268›Full record

ArticleThe Biochemical journal2018

A transcription factor network represses

Michael J Mutolo, Shih-Hsing Leir, Sara L Fossum, James A Browne, Ann Harris

Open access · bronzeAbstract read
In one paragraph

Article in The Biochemical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Review
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  9. Article
  10. Tissue-Specific Regulation ofInternational journal of molecular sciences · 2023
    Review
  11. Cellular heterogeneity in the 16HBE14oPhysiological reports · 2023
    Article
  12. Article
  13. Article
  14. CFTR and Gastrointestinal Cancers: An Update.Journal of personalized medicine · 2022
    Review
  15. Revisiting CFTR Interactions: Old Partners and New Players.International journal of molecular sciences · 2021
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Michael J MutoloHuman Molecular Genetics Program, Lurie Children's Research Center, Chicago, IL 60614, U.S.A.
Shih-Hsing LeirHuman Molecular Genetics Program, Lurie Children's Research Center, Chicago, IL 60614, U.S.A.
Sara L FossumHuman Molecular Genetics Program, Lurie Children's Research Center, Chicago, IL 60614, U.S.A.
James A BrowneHuman Molecular Genetics Program, Lurie Children's Research Center, Chicago, IL 60614, U.S.A.
Ann HarrisHuman Molecular Genetics Program, Lurie Children's Research Center, Chicago, IL 60614, U.S.A. ann.harris@case.edu.
Northwestern University · US

Funding

Vector CoreP30DK065988 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Richard Charles Boucher, Martina Gentzsch · 2004 to 2026
$26.5M
Tissue-specific regulation of a gene essential for normal airway epitheliaR01HL094585 · NHLBI · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI HARRIS, ANN · 2009 to 2020
$2.9M
Mining open chromatin to define molecular mechanisms of CF modifier genesR01HL117843 · NHLBI · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI HARRIS, ANN, KNOWLES, MICHAEL R · 2013 to 2017
$2.9M
Transcriptional Networks Regulating Luminal Environment in the EpididymisR01HD068901 · NICHD · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI HARRIS, ANN · 2011 to 2023
$2.8M
The Role of the EHF Transcription Factor in Lung Epithelial FunctionF30HL124925 · NHLBI · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI FOSSUM, SARA · 2015 to 2016
$85k
NHLBI NIH HHS F30 HL124925NHLBI NIH HHS R01 HL094585NHLBI NIH HHS R01 HL117843NICHD NIH HHS R01 HD068901NIDDK NIH HHS P30 DK065988
6 · The paper itself

Abstract

Mutations in the cystic fibrosis transmembrane conductance regulator (

Indexed as

Gene Expression RegulationGene Regulatory NetworksRegulatory Sequences, Nucleic AcidBronchiCells, CulturedCystic Fibrosis Transmembrane Conductance RegulatorEpithelial CellsHumansTranscription FactorsCFTR protein, humanCystic Fibrosis Transmembrane Conductance RegulatorTranscription Factorscystic fibrosis transmembrane conductance regulatorEHFgene expression and regulationKLF5lung epitheliumtranscription factors

Identifiers

PMID29572268
PMCPMC6380350
OpenAlexW2791254622

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.