Evidence map›Paper›PMID 29571708›Full record

ArticleJournal of theoretical biology2018

High dimensional random walks can appear low dimensional: Application to influenza H3N2 evolution.

James Moore, Hasan Ahmed, Rustom Antia

Abstract read
In one paragraph

Article in Journal of theoretical biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Phantom oscillations in principal component analysis.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

James MooreDepartment of Biology, Emory University, Atlanta, GA, USA. Electronic address: j.r.moore@emory.edu.
Hasan AhmedDepartment of Biology, Emory University, Atlanta, GA, USA.
Rustom AntiaDepartment of Biology, Emory University, Atlanta, GA, USA.

Funding

Understanding Transmission with Integrated Genetic and Epidemiologic InferenceU54GM111274 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BEDFORD, TREVOR BC · 2014 to 2018
$12.5M
Modeling the dynamics and evolution of immune responses to influenza virusesU19AI117891 · NIAID · EMORY UNIVERSITY · PI AHMED, RAFI, ANTIA, RUSTOM NOSHIR · 2015 to 2019
$8.4M
QUANTIFYING THE BALANCE BETWEEN VACCINE-INDUCED T CELL PROTECTION AND PATHOLOGYR01AI110720 · NIAID · EMORY UNIVERSITY · PI ANTIA, RUSTOM NOSHIR · 2014 to 2018
$2.0M
NIAID NIH HHS R01 AI110720NIAID NIH HHS U19 AI117891NIGMS NIH HHS U54 GM111274
6 · The paper itself

Abstract

One important feature of the mammalian immune system is the highly specific binding of antigens to antibodies. Antibodies generated in response to one infection may also provide some level of cross immunity to other infections. One model to describe this cross immunity is the notion of antigenic space, which assigns each antibody and each virus a point in R

Indexed as

Evolution, MolecularAnimalsAntigens, ViralGenetic DriftHemagglutinin Glycoproteins, Influenza VirusHumansInfluenza A Virus, H3N2 SubtypeInfluenza, HumanRandom AllocationAntigens, ViralHemagglutinin Glycoproteins, Influenza VirusAntigenic cartographyMulti-dimensional scalingPrincipal component analysis

Identifiers

PMID29571708
PMCPMC5913756

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.