ArticleClinical pharmacology and therapeutics2018
Patient Enrichment for Precision-Based Cancer Clinical Trials: Using Prospective Cohort Surveillance as an Approach to Improve Clinical Trials.
Article in Clinical pharmacology and therapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Clinical Trial Perceptions Among Patients Enrolled in a Precision Oncology Protocol at an Appalachian-Serving Cancer Center.Psycho-oncology · 2026Article
- The Oncology Research Information Exchange Network (ORIEN) - Building a Real-World Collaborative, Patient-driven Infrastructure for Discovery Research and Precision Oncology.Research square · 2026Article
- Causal Effects of Hydrophilic Bile Acids on Carfilzomib-Related Cardiovascular Events in Multiple Myeloma: A Mendelian Randomization Study.Clinical pharmacology and therapeutics · 2026Article
- Intrinsic tumor factors and extrinsic environmental and social exposures contribute to endometrial cancer recurrence patterns.Research square · 2026Article
- Germline whole-exome sequencing revealsJournal for immunotherapy of cancer · 2025Article
- Training, Validating, and Testing Machine Learning Prediction Models for Endometrial Cancer Recurrence.JCO precision oncology · 2025Article
- The Tumor Microbiome as a Predictor of Outcomes in Patients with Metastatic Melanoma Treated with Immune Checkpoint Inhibitors.Cancer research communications · 2024Article
- The Tumor Microbiome Reacts to Hypoxia and Can Influence Response to Radiation Treatment in Colorectal Cancer.Cancer research communications · 2024Article
- Inherited Germline Variants in Urinary Tract Cancer: A Multicenter Whole-Exome Sequencing Analysis and Correlation With Clinical Features and Tumor Genomics.JCO precision oncology · 2024Article
- Article
- Exogenous Sequences in Tumors and Immune Cells (Exotic): A Tool for Estimating the Microbe Abundances in Tumor RNA-seq Data.Cancer research communications · 2023Article
- The tumor microbiome as a predictor of outcomes in patients with metastatic melanoma treated with immune checkpoint inhibitors.bioRxiv : the preprint server for biology · 2023Article
- A bioinformatics tool for identifying intratumoral microbes from the ORIEN dataset.bioRxiv : the preprint server for biology · 2023Article
- Whole-Exome sequencing analysis identified TMSB10/TRABD2A locus to be associated with carfilzomib-related cardiotoxicity among patients with multiple myeloma.Frontiers in cardiovascular medicine · 2023Article
- Factors Predicting Participation in the Prospective Genomic Sequencing Study, Total Cancer Care (TCC), in Kentucky.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2022Article
- Real-World Evaluation of Universal Germline Screening for Cancer Treatment-Relevant Pharmacogenes.Cancers · 2021Article
- Cohort Identification for Translational Bioinformatics Studies.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Recommendations for patient similarity classes: results of the AMIA 2019 workshop on defining patient similarity.Journal of the American Medical Informatics Association : JAMIA · 2020Article
- TENET 2.0: Identification of key transcriptional regulators and enhancers in lung adenocarcinoma.PLoS genetics · 2020Article
- The Community Oncology and Academic Medical Center Alliance in the Age of Precision Medicine: Cancer Genetics and Genomics Considerations.Journal of clinical medicine · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Technological advances have led to the identification of biomarkers and development of novel target-based therapies. While some novel therapies have improved patient outcomes, the prevalence and diversity of biomarkers and targets in patient populations, especially patients with cancer, has created a challenge for the design and performance of clinical trials. To address this challenge we propose that prospective cohort surveillance of patients may be a solution to promote clinical trial matching for patients in need.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.