Evidence map›Paper›PMID 29570682›Full record

ArticleGenes2018

Resistance to 6-Methylpurine is Conferred by Defective Adenine Phosphoribosyltransferase in Tetrahymena.

Takahiko Akematsu, Andrew Findlay, Yasuhiro Fukuda, Ronald E Pearlman, Josef Loidl, Eduardo Orias, Eileen P Hamilton

Open access · goldAbstract read
In one paragraph

Article in Genes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Takahiko AkematsuDepartment of Chromosome Biology, University of Vienna, 1030 Vienna, Austria. takahiko.akematsu@univie.ac.at.ORCID 0000-0001-9396-0243
Andrew FindlayDepartment of Molecular, Cellular and Developmental Biology, University of California at Santa Barbara, Santa Barbara, CA 93106, USA. arfindlay@wustl.edu.
Yasuhiro FukudaDepartment of Biodiversity Science, Division of Biological Resource Science, Graduate School of Agricultural Science, Tohoku University, Oosaki 989-6711, Japan. yasuhiro.fukuda.b7@tohoku.ac.jp.
Ronald E PearlmanDepartment of Biology, York University, Toronto, ON M3J 1P3, Canada. ronp@yorku.ca.
Josef LoidlDepartment of Chromosome Biology, University of Vienna, 1030 Vienna, Austria. josef.loidl@univie.ac.at.ORCID 0000-0002-2519-4484
Eduardo OriasDepartment of Molecular, Cellular and Developmental Biology, University of California at Santa Barbara, Santa Barbara, CA 93106, USA. eduardo.orias@lifesci.ucsb.edu.
Eileen P HamiltonDepartment of Molecular, Cellular and Developmental Biology, University of California at Santa Barbara, Santa Barbara, CA 93106, USA. eileen.hamilton@lifesci.ucsb.edu.
University of California, Santa Barbara · USUniversity of Vienna · ATTohoku University · JPYork University · CA

Funding

Austrian Science Fund FWF P 27313
6 · The paper itself

Abstract

6-methylpurine (6mp) is a toxic analog of adenine that inhibits RNA and protein synthesis and interferes with adenine salvage mediated by adenine phosphoribosyltransferase (APRTase). Mutants of the ciliated protist

Indexed as

6-methylpurineadenine phosphoribosyltransferasemutationselection markerTetrahymena thermophila

Identifiers

PMID29570682
PMCPMC5924521
OpenAlexW2790087917

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.