ArticleInternational braz j urol : official journal of the Brazilian Society of Urology
The history of varicocele: from antiquity to the modern ERA.
Article in International braz j urol : official journal of the Brazilian Society of Urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Surgical or radiological treatment for varicoceles in subfertile men.The Cochrane database of systematic reviews · 2021Pooled it
- Evaluating Silicone Gel Efficacy in Reducing Scar Formation Following Microscopic Inguinal Varicocelectomy: A Double-Blind Prospective Controlled Trial.International wound journal · 2025Trial
- Comparison of transbrachial and transfemoral venous access in varicocele embolization: impact on radiation dose and technical success.European radiology · 2026Article
- Adolescent varicocele, a Gordian knot: A comprehensive review of clinical perspectives and future directions.World journal of methodology · 2026Review
- Trends for Surgical Treatment of Testicular Varicocele: A German Whole-population Analysis of Inpatient Procedures from 2006 to 2021.European urology open science · 2025Article
- Outcome following the surgical management of varicocele in children and adolescents: a systematic review and meta-analysis.Therapeutic advances in urologyArticle
- Development and validation a task-specific checklist for a microsurgical varicocelectomy simulation model.International braz j urol : official journal of the Brazilian Society of UrologyArticle
- What does a varicocele do to a man's fertility? There is much more than meets the eye.International braz j urol : official journal of the Brazilian Society of UrologyArticle
- From pathophysiology to practice: addressing oxidative stress and sperm DNA fragmentation in Varicocele-affected subfertile men.International braz j urol : official journal of the Brazilian Society of UrologyReview
- The obesity paradox in varicocele - is the protective effect real?International braz j urol : official journal of the Brazilian Society of UrologyArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Men have most likely been affected by varicocele since the assumption of the upright position. In De Medicina, written during the first century AD, Celsus credits the Greeks with the first description of a varicocele, and he recorded his own acute observation: "The veins are swollen and twisted over the testicle, which becomes smaller". Celsus himself is credited with the distinction between varicocele (dilation of surface veins) and "cirsocele" (dilation of deep veins). There has been a long history of treatment attempts and failures, some of which are remarkably strange, that have sometimes culminated in tragedy, as in the case of French professor Jacques-Mathieu Delpech (1772- 1832). Although some questions regarding the etiopathology and treatment of varicocele remain unanswered, a succession of more or less conservative attempts involving all medical cultures has been performed throughout history. The report by W.S. Tulloch in 1952 brought varicocele into the era of modern evidence-based medicine, and varicocele surgery finally progressed beyond the aim of merely relieving scrotal pain and swelling. From 1970 to 2000, varicocelectomies gained worldwide attention for the treatment of male infertility. Several innovative procedures to correct varicoceles began to appear in the world's literature as interventional radiology, microsurgery, laparoscopy, and robotics, while comprehensive review articles were also published on the subject of varicocelectomies. Microsurgery is nowadays used worldwide and it can be considered to be the gold standard for correcting infertility linked to varicocele.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.