ArticleInternational braz j urol : official journal of the Brazilian Society of Urology
Diagnostic accuracy of multiparametric magnetic resonance imaging in detecting extracapsular extension in intermediate and high - risk prostate cancer.
Article in International braz j urol : official journal of the Brazilian Society of Urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 6 of them syntheses that pooled it.
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16 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- 10 mm (PI-RADS v2.1) versus 15 mm (PI-RADS v1.0) tumor capsule contact length in predicting extracapsular extension in prostate cancer: Meta-analysis and systematic review.Abdominal radiology (New York) · 2025Pooled it
- The Role of Magnetic Resonance Imaging and Positron Emission Tomography/Computed Tomography in the Primary Staging of Newly Diagnosed Prostate Cancer: A Systematic Review of the Literature.European urology oncology · 2021Pooled it
- The Quantitative Assessment of Using Multiparametric MRI for Prediction of Extraprostatic Extension in Patients Undergoing Radical Prostatectomy: AFrontiers in oncology · 2021Pooled it
- Imaging for Metastasis in Prostate Cancer: A Review of the Literature.Frontiers in oncology · 2020Pooled it
- Accuracy of multiparametric magnetic resonance imaging for diagnosing prostate Cancer: a systematic review and meta-analysis.BMC cancer · 2019Pooled it
- Accuracy of multiparametric magnetic resonance imaging for detecting extracapsular extension in prostate cancer: a systematic review and meta-analysis.The British journal of radiology · 2019Pooled it
- Article
- The Role of Salvage Radical Prostatectomy in Patients with Radiation-Resistant Prostate Cancer.Cancers · 2023Review
- Quantitative imaging parameters to predict the local staging of prostate cancer in intermediate- to high-risk patients.Insights into imaging · 2022Article
- Current Opinion on the Use of Magnetic Resonance Imaging in Staging Prostate Cancer: A Narrative Review.Cancer management and research · 2022Review
- MRI and Targeted Biopsy Essential Tools for an Accurate Diagnosis and Treatment Decision Making in Prostate Cancer.Diagnostics (Basel, Switzerland) · 2021Review
- The absolute tumor-capsule contact length in the diagnosis of extraprostatic extension of prostate cancer.Abdominal radiology (New York) · 2021Article
- Extracapsular extension on multiparametric magnetic resonance imaging better predicts pT3 disease at radical prostatectomy compared to perineural invasion on biopsy.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2021Article
- Magnetic resonance imaging improves the prediction of tumor staging in localized prostate cancer.Abdominal radiology (New York) · 2021Article
- Apparent diffusion coefficient in extraprostatic extension of prostate cancer: a systematic review and diagnostic meta-analysis.Cancer management and research · 2019Article
- Does mpMRI guidance improve HIFU partial gland ablation compared to conventional ultrasound guidance? Early functional outcomes and complications from a single center.International braz j urol : official journal of the Brazilian Society of UrologyArticle
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11 authors.
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No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the diagnostic performance of preoperative multiparametric magnetic resonance imaging (mp-MRI) as a predictor of extracapsular extension (ECE) and unfavorable Gleason score (GS) in patients with intermediate and high-risk prostate cancer (PCa). MATERIALS AND
methodsPatients with clinically localized PCa who underwent radical prostatectomy (RP) and had preoperative mp-MRI between May-2011 and December-2013. Mp-MRI was evaluated according to the European Society of Urogenital Radiology MRI prostate guidelines by two different readers. Histopathological RP results were the standard reference.
results79 patients were included; mean age was 61 and median preoperative prostate-specific antigen (PSA) 7.0. On MRI, 28% patients had ECE evidenced in the mp-MRI, 5% seminal vesicle invasion (SVI) and 4% lymph node involvement (LNI). At RP, 39.2% had ECE, 26.6% SVI and 12.8% LNI. Sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV) of mp-MRI for ECE were 54.9%, 90.9%, 76%, 81% and 74.1% respectively; for SVI values were 19.1%, 100%, 77.3%, 100% and 76.1% respectively and for LNI 20%, 98.4%, 86.7%, 66.7% and 88.7%.
conclusionsMajor surgical decisions are made with digital rectal exam (DRE) and ultrasound studies before the use of Mp-MRI. This imaging study contributes to rule out gross extraprostatic extension (ECE, SVI, LNI) without competing with pathological studies. The specificity and NPV are reasonable to decide surgical approach. A highly experienced radiology team is needed to provide accurate estimations of tumor extension and aggressiveness.
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