ReviewObesity (Silver Spring, Md.)2018
Young Adult Cancer: Influence of the Obesity Pandemic.
Review in Obesity (Silver Spring, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Economic costs of obesity: a systematic review.International journal of obesity (2005) · 2024Pooled it
- Black American and Latinx Parent/Caregiver Participation in Digital Health Obesity Interventions for Children: A Systematic Review.Frontiers in digital health · 2021Pooled it
- Global, regional and time-trend prevalence of central obesity: a systematic review and meta-analysis of 13.2 million subjects.European journal of epidemiology · 2020Pooled it
- Oxytocin receptor signaling contributes to the mitochondrial integrity and maintain gastric mucosal homeostasis in male mice.iScience · 2026Article
- Built and socioeconomic environment: associations with cancer-risk health behaviors among healthy emerging adults.Journal of behavioral medicine · 2026Article
- Early-onset cancer and modifiable risk: quantifying the combined impact of excess body weight and alcohol on breast and colorectal cancer in Italy (18-34 years).BMC public health · 2026Article
- Synergistic associations of metformin and GLP-1 receptor agonist use with adiposity-related cancer incidence in people living with type 2 diabetes.Diabetes, obesity & metabolism · 2026Article
- Positive Association Between Body Mass Index and the Likelihood of Reporting an Overall Cancer Diagnosis Among College Students in the United States.Cancer medicine · 2026Article
- Demonstrating trends for early colorectal cancer incidence: a retrospective analysis of patients in Northwest Ohio.Frontiers in oncology · 2026Article
- Long-Term Cancer Incidence Trends in Korea (2001-2020): An Age-Period-Cohort and Joinpoint Analysis with a Focus on Younger Cohorts.Medicina (Kaunas, Lithuania) · 2025Article
- Childhood obesity management in primary care: Bridging guidelines and practice.Obesity pillars · 2025Article
- Adipocytes enhance tongue cancer progression potentially via IL-6 and extracellular vesicles.Scientific reports · 2025Article
- Examining the continuity of modifiable cancer-risk behaviors from youth into adulthood through prospective longitudinal studies: A scoping review.Social science & medicine (1982) · 2025Article
- Global cancer mortality among children, adolescents, and young adults from 77 countries, 1990-2021: a global time-series analysis and modelling study.World journal of pediatrics : WJP · 2025Article
- Contemporary Changes in Global Trends in Early-Onset Cancer: Incidence and Mortality (2000-2021).Cancers · 2025Article
- Trends in the prevalence of early-onset cancer and associated early-life exposures among US adults: A serial cross-sectional study.Preventive medicine reports · 2025Article
- Engagement with Digital Weight Loss Intervention Components and Weight Outcomes.Journal of technology in behavioral science · 2024Article
- Rising incidence of obesity-related cancers among younger adults in China: A population-based analysis (2007-2021).Med (New York, N.Y.) · 2024Article
- Metabolic Dysregulation and Cancer Risk Program (MeDOC): a transdisciplinary approach to obesity-associated cancers.Journal of the National Cancer Institute · 2024Article
- Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
objectiveThe purpose of this article is to review the association of the obesity pandemic with appearance of cancers in young adults under age 50 and to define potential mechanisms by which obesity may accelerate the development of malignancy.
methodsA comprehensive narrative review was performed to integrate preclinical, clinical, and epidemiologic evidence describing the association of obesity with cancer in young adults based on a search of PubMed and Google databases.
resultsResults from more than 100 publications are summarized. Although they differ in age groups analyzed and incidence of obesity, sufficient data exists to suggest an influence of the obesity pandemic on the increase of cancer among young adults.
conclusionsCancer in young adults is occurring with increasing frequency. Overweight and obesity have become major public health issues reaching pandemic proportions. Excess weight is associated with increased cancer risk, morbidity, and mortality. Multiple murine models indicate that obesity not only increases cancer incidence but also accelerates its development. Thus, the possibility exists that overweight and obesity may be contributing to the appearance of specific malignancies at younger ages. This prospect, in association with the worldwide expansion of obesity, suggests an impending explosive increase in obesity-associated cancers in young adults.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.