ArticleThe Plant journal : for cell and molecular biology2018
Direct production of dihydroxylated sesquiterpenoids by a maize terpene synthase.
Article in The Plant journal : for cell and molecular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 35 citations in OpenAlex.
- Terpene synthases screening in agarwood treeSynthetic and systems biotechnology · 2027Article
- Reinvestigation of the mechanism and selectivity of 1,8-cineole synthase usingChemical science · 2026Article
- Structural Revision of the CAngewandte Chemie (International ed. in English) · 2026Article
- Characterization of an (E, E)-farnesyl pyrophosphate synthase in Saxifraga stolonifera involved in triterpenoid biosynthesis.Plant molecular biology · 2026Article
- Synthesis of depressin, cryptomeridiol and 4-Beilstein journal of organic chemistry · 2026Article
- The role of isoprenoids in the chemical interaction between plants and other organisms in their rhizosphere.aBIOTECH · 2025Review
- Genome-wide analysis of terpene synthase family in peanut (Arachis hypogaea L.) explores the potential cross-talk in terpenoid biosynthesis.BMC genomics · 2025Article
- The terpene synthase gene family in maize - a clarification of existing community nomenclature.BMC genomics · 2023Article
- Decoding Catalysis by Terpene Synthases.ACS catalysis · 2023Review
- Disease resistance conferred by components of essential chrysanthemum oil and the epigenetic regulation of OsTPS1.Science China. Life sciences · 2023Article
- Maize Terpene Synthase 8 (ZmTPS8) Contributes to a Complex Blend of Fungal-Elicited Antibiotics.Plants (Basel, Switzerland) · 2023Article
- Hedycaryol - Central Intermediates in Sesquiterpene Biosynthesis, Part II.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022Review
- Unoccupied aerial systems discovered overlooked loci capturing the variation of entire growing period in maize.The plant genome · 2021Article
- Engineering of Ancestors as a Tool to Elucidate Structure, Mechanism, and Specificity of Extant Terpene Cyclase.Journal of the American Chemical Society · 2021Article
- Direct formation of the sesquiterpeonid ether liguloxide by a terpene synthase in Senecio scandens.Plant molecular biology · 2021Article
- The reconstruction and biochemical characterization of ancestral genes furnish insights into the evolution of terpene synthase function in the Poaceae.Plant molecular biology · 2020Article
- Probing Enzymatic Structure and Function in the Dihydroxylating Sesquiterpene Synthase ZmEDS.Biochemistry · 2020Article
- The foxtail millet (Setaria italica) terpene synthase gene family.The Plant journal : for cell and molecular biology · 2020Article
- Article
- Sixty-One Volatiles Have Phylogenetic Signals Across Bacterial Domain and Fungal Kingdom.Frontiers in microbiology · 2020Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
The astounding structural and biological diversities of the large class of terpenoid natural products are imparted by both their complex hydrocarbon backbones and further elaboration by the addition of multiple hydroxyl groups, which provide both solubility and specific binding properties. While the role of terpene synthases (TPSs) in generating hydrocarbons with complex backbones is well known, these also are known to generate (singly) hydroxylated products by the addition of water prior to terminating deprotonation. Here a maize sesquiterpene synthase was unexpectedly found to generate dually hydroxylated products directly from (E,E)-farnesyl diphosphate, primarily eudesmane-2,11-diol, along with two closely related structural isomers. The unprecedented formation of these diols was proposed to proceed via initial addition of water to a germacradienyl
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.