Evidence map›Paper›PMID 29570206›Full record

ArticleCardiovascular journal of Africa

Participation in research improves overall patient management: insights from the Global Rheumatic Heart Disease registry (REMEDY).

E A Prendergast, S Perkins, M E Engel, B Cupido, V Francis, A Joachim, M Al Kebsi, F Bode-Thomas, A Damasceno, A Abul Fadl and 13 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiovascular journal of Africa. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

E A PrendergastDepartment of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
S PerkinsDepartment of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
M E EngelDepartment of Medicine, Groote Schuur Hospital, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
B CupidoDivision of Cardiology, Groote Schuur Hospital, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
V FrancisDepartment of Medicine, Groote Schuur Hospital, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
A JoachimDepartment of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
M Al KebsiFaculty of Medicine and Surgery, University of Sana'a, Al-Thawrah, Cardiac Centre, Sana'a, Yemen.
F Bode-ThomasDepartments of Paediatrics, University of Jos and Jos University Teaching Hospital, Jos, Nigeria.
A DamascenoDepartment of Medicine, Eduardo Mondlane University, Maputo, Mozambique.
A Abul FadlFaculty of Medicine, Benha University, Cairo, Egypt.
A El SayedCardiothoracic Surgery Department, Al Shaab Teaching Hospital and Faculty of Medicine, Alzaiem Alazhari University, Khartoum, Sudan.
B GituraCardiology Unit, Department of Medicine, Kenyatta National Teaching and Referral Hospital, Nairobi, Kenya.
N KennedyDepartment of Paediatrics and Child Health, College of Medicine, University of Malawi, Blantyre, Malawi; Centre for Medical Education, Queen's University, Belfast; Royal Belfast Hospital for Sick Children, Belfast, Ireland.
A IbrahimCardiothoracic Surgery Department, Al Shaab Teaching Hospital and Faculty of Medicine, Alzaiem Alazhari University, Khartoum, Sudan.
J MucumbitsiPaediatric Cardiology Unit, Department of Paediatrics, King Faisal Hospital, Kigali, Rwanda.
A M AdeoyeDivision of Cardiology, Department of Medicine, University College Hospital, Ibadan, Nigeria.
J MusukuUniversity Teaching Hospital, Department of Paediatrics and Child Health, University of Zambia, Lusaka, Zambia.
E OkelloUganda Heart Institute, Kampala, Uganda.
T OlunugaDepartment of Medicine, Federal Medical Centre, Abeokuta, Nigeria.
S ShetaDepartment of Paediatrics, Division of Paediatric Cardiology, Faculty of Medicine, Cairo University Children's Hospital, Cairo, Egypt.
B M MayosiDepartment of Medicine, Groote Schuur Hospital, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; Division of Cardiology, Groote Schuur Hospital, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; Dean of Faculty of Health Sciences, University of Cape Town, South Africa.
L J ZühlkeDepartment of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; Department of Medicine, Groote Schuur Hospital, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; Division of Cardiology, Groote Schuur Hospital, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa. Email: Liesl.zuhlke@uct.ac.za.
REMEDY investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRheumatic heart disease (RHD) is a major public health problem in low- and middle-income countries (LIMCs), with a paucity of high-quality trial data to improve patient outcomes. Investigators felt that involvement in a recent large, observational RHD study impacted positively on their practice, but this was poorly defined.

aimThe purpose of this study was to document the experience of investigators and research team members from LMICs who participated in a prospective, multi-centre study, the global Rheumatic Heart Disease Registry (REMEDY), conducted in 25 centres in 14 countries from 2010 to 2012.

methodWe conducted an online survey of site personnel to identify and quantify their experiences. Telephone interviews were conducted with a subset of respondents to gather additional qualitative data. We asked about their experiences, positive and negative, and about any changes in RHD management practices resulting from their participation in REMEDY as a registry site.

resultsThe majority of respondents in both the survey and telephone interviews indicated that participation as a registry site improved their management of RHD patients. Administrative changes included increased attention to follow-up appointments and details in patient records. Clinical changes included increased use of penicillin prophylaxis, and more frequent INR monitoring and contraceptive counselling.

conclusionOur study demonstrates that participation in clinical research on RHD can have a positive impact on patient management. Furthermore, REMEDY has led to increased patient awareness and improved healthcare workers' knowledge and efficiency in caring for RHD patients.

Indexed as

Attitude of Health PersonnelDelivery of Health Care, IntegratedHealth Knowledge, Attitudes, PracticePractice Patterns, Physicians'Research DesignClinical CompetenceHealth Care SurveysHumansInterviews as TopicQuality ImprovementQuality Indicators, Health CareRegistriesResearch PersonnelRheumatic Heart Disease

Identifiers

PMID29570206
PMCPMC6008904

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.