Evidence map›Paper›PMID 29569959›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2018

Noninvasive assessment of the common carotid artery hemodynamics with increasing exercise work rate using wave intensity analysis.

N Pomella, E N Wilhelm, C Kolyva, J González-Alonso, M Rakobowchuk, A W Khir

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Detecting heart failure from B-mode ultrasound characterization of arterial pulse waves.American journal of physiology. Heart and circulatory physiology · 2024
    Article
  5. A computational study of aortic reconstruction in single ventricle patients.Biomechanics and modeling in mechanobiology · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

N PomellaInstitute of Environment, Health and Societies, Biomedical Engineering Research Theme, Brunel University London , Middlesex , United Kingdom.
E N WilhelmCentre for Human Performance, Exercise and Rehabilitation, College of Health and Life Sciences, Brunel University London , Middlesex , United Kingdom.ORCID 0000-0003-2679-0744
C KolyvaInstitute of Environment, Health and Societies, Biomedical Engineering Research Theme, Brunel University London , Middlesex , United Kingdom.
J González-AlonsoCentre for Human Performance, Exercise and Rehabilitation, College of Health and Life Sciences, Brunel University London , Middlesex , United Kingdom.
M RakobowchukCentre for Human Performance, Exercise and Rehabilitation, College of Health and Life Sciences, Brunel University London , Middlesex , United Kingdom.ORCID 0000-0002-1965-3277
A W KhirInstitute of Environment, Health and Societies, Biomedical Engineering Research Theme, Brunel University London , Middlesex , United Kingdom.
Brunel University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noninvasively determined local wave speed ( c) and wave intensity (WI) parameters provide insights into arterial stiffness and cardiac-vascular interactions in response to physiological perturbations. However, the effects of incremental exercise and subsequent recovery on c and WI have not been fully established. We examined the changes in c and WI parameters in the common carotid artery (CCA) during exercise and recovery in eight young, healthy male athletes. Ultrasound measurements of CCA diameter and blood flow velocity were acquired at rest, during five stages of incremental exercise (up to 70% maximum work rate), and throughout 1 h of recovery, and noninvasive WI analysis [diameter-velocity ( DU) approach] was performed. During exercise, c increased (+136%), showing increased stiffness with work rate. All peak and area of forward compression, backward compression, and forward expansion waves increased during exercise (+452%, +700%, and +900%, respectively). However, WI reflection indexes and CCA resistance did not significantly change from rest to exercise. Furthermore, wave speed and the magnitude of all waves returned to baseline within 5 min of recovery, suggesting that the effects of exercise in the investigated parameters of young, healthy individuals were transient. In conclusion, incremental exercise was associated with an increase in local CCA stiffness and increases in all wave parameters, indicative of enhanced ventricular contractility and improved late-systolic blood flow deceleration. NEW & NOTEWORTHY We examined hemodynamics of the common carotid artery using noninvasive application of wave intensity analysis during exercise and recovery. The hemodynamic adjustments to exercise were associated with increases in local common carotid artery stiffness and all waves' parameters, with the latter indicating enhanced ventricular contractility and improved late systolic blood flow deceleration.

Indexed as

ExerciseHemodynamicsAdultCarotid Artery, CommonHumansMalearterial distensibilityincremental exerciselnDU loopreflection indexwave speed

Identifiers

PMID29569959
PMCPMC6139620
OpenAlexW2792943907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.