Evidence map›Paper›PMID 29569954›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2018

Nitrosative stress uncovers potent β

Mary D Frame, Anthony M Dewar, Rhodora C Calizo, Androniqi Qifti, Suzanne F Scarlata

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mary D FrameDepartment of Biomedical Engineering, Stony Brook University , Stony Brook, New York.ORCID 0000-0003-3890-2221
Anthony M DewarDepartment of Biomedical Engineering, Stony Brook University , Stony Brook, New York.
Rhodora C CalizoDepartment of Physiology and Biophysics, Stony Brook University , Stony Brook, New York.
Androniqi QiftiDepartment of Chemistry and Biochemistry Worcester Polytechnic Institute , Worcester, Massachusetts.
Suzanne F ScarlataDepartment of Physiology and Biophysics, Stony Brook University , Stony Brook, New York.
Stony Brook University · USWorcester Polytechnic Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the effect of sodium nitroprusside (SNP) preexposure on vasodilation via the β-adrenergic receptor (BAR) system. SNP was used as a nitrosative/oxidative proinflammatory insult. Small arterioles were visualized by intravital microscopy in the hamster cheek pouch tissue (isoflurane, n = 45). Control dilation to isoproterenol (EC

Indexed as

EndocytosisNitrosative StressVasodilationAnimalsArteriolesCheekClathrin-Coated VesiclesCricetinaeDose-Response Relationship, DrugDynaminsEndosomesHeLa CellsHumansIn Vitro TechniquesMaleOxidative StressDynaminsReceptors, Adrenergic, beta-2Vasodilator Agentsclathrin endosome formationcurcumininflammationpreconditioningβ-adrenergic receptor

Identifiers

PMID29569954
PMCPMC6415737
OpenAlexW2789772034

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.