ArticleHuman brain mapping2018
Anterior insula hyperactivation in ADHD when faced with distracting negative stimuli.
Article in Human brain mapping, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Emotion processing difficulties in ADHD: a Bayesian meta-analysis study.European child & adolescent psychiatry · 2025Pooled it
- Annual Research Review: What processes are dysregulated among emotionally dysregulated youth? - a systematic review.Journal of child psychology and psychiatry, and allied disciplines · 2025Pooled it
- Meta-analysis of structural and functional alterations of brain in patients with attention-deficit/hyperactivity disorder.Frontiers in psychiatry · 2022Pooled it
- Emotional scene processing in children and adolescents with attention deficit/hyperactivity disorder: a systematic review.European child & adolescent psychiatry · 2021Pooled it
- Exploring central sensitization symptoms in children with ADHD and their parents: a case-control study.BMC psychiatry · 2026Article
- Parental high-fat/high-sugar diets and their lasting impact on brain development in offspring: a longitudinal mouse MRI study.Translational psychiatry · 2025Article
- Emotional wellbeing in neurodivergent populations.Frontiers in psychology · 2025Article
- Abnormal stability of dynamic functional architecture in drug-naïve children with attention-deficit/hyperactivity disorder.BMC psychiatry · 2024Article
- Unique versus shared neural correlates of externalizing psychopathology in late childhood.Journal of psychopathology and clinical science · 2024Article
- Simultaneous cluster structure learning and estimation of heterogeneous graphs for matrix-variate fMRI data.Biometrics · 2023Article
- Neural Basis of Internal Attention in Adults with Pure and Comorbid ADHD.Journal of attention disorders · 2023Article
- Case report: Methylphenidate improved chronic pain in an adult patient with attention deficit hyperactivity disorder.Frontiers in psychiatry · 2023Article
- Pain hypersensitivity in a pharmacological mouse model of attention-deficit/hyperactivity disorder.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Structural brain correlates of burnout severity in medical professionals: A voxel-based morphometric study.Neuroscience letters · 2022Article
- Abnormal degree centrality in first-episode medication-free adolescent depression at rest: A functional magnetic resonance imaging study and support vector machine analysis.Frontiers in psychiatry · 2022Article
- Neural Correlates of Reactive Aggression in Adult Attention-Deficit/Hyperactivity Disorder.Frontiers in psychiatry · 2022Article
- The neurobiology of misophonia and implications for novel, neuroscience-driven interventions.Frontiers in neuroscience · 2022Review
- Front and center: Maturational dysregulation of frontal lobe functional neuroanatomic connections in attention deficit hyperactivity disorder.Frontiers in neuroanatomy · 2022Article
- Brain morphometric abnormalities in boys with attention-deficit/hyperactivity disorder revealed by sulcal pits-based analyses.CNS neuroscience & therapeutics · 2021Article
- Altered brain morphology in boys with attention deficit hyperactivity disorder with and without comorbid conduct disorder/oppositional defiant disorder.Human brain mapping · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with attention deficit hyperactivity disorder (ADHD) suffer from poor emotion regulation that might arise from problems in the distribution of attentional resources when confronted with emotional distractors. Previous studies investigating the neurocognitive basis of these problems remain inconclusive. Moreover, most of these studies did not exclude participants with comorbidity, particularly of conduct or oppositional defiant disorder. The aim of this study was to assess alterations in fronto-limbic activation in ADHD adolescents specifically during negative distractors in an emotional attention task. For this purpose, we used functional magnetic resonance imaging to assess 25 boys with noncomorbid ADHD and 25 typically developing (TD) boys while they performed an emotional attention task with positive, negative, and neutral emotional distractors. Boys with ADHD had increased activation relative to TD boys specifically during the negative valenced stimuli in an emotional processing network comprising left anterior insula reaching into the inferior frontal gyrus. The findings suggest altered salience processing in ADHD of negative valenced emotional stimuli that may lead to higher distractibility in ADHD specifically when faced with negative emotional distractors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.