ReviewImmunology and cell biology2018
Development of mucosal-associated invariant T cells.
Review in Immunology and cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed.
- Review
- The NF-κB transcription factor RelA directs mucosal-associated invariant T-cell development.Immunology and cell biology · 2026Article
- Metabolic control of innate-like T cells.Nature reviews. Immunology · 2026Review
- Insights into the tissue repair features of MAIT cells.Frontiers in immunology · 2024Review
- Thymic development of human natural killer T cells: recent advances and implications for immunotherapy.Frontiers in immunology · 2024Review
- Current Perspectives and Challenges of MAIT Cell-Directed Therapy for Tuberculosis Infection.Pathogens (Basel, Switzerland) · 2023Review
- Transcriptomes and metabolism define mouse and human MAIT cell populations.Science immunology · 2023Article
- TAK1 is essential for MAIT cell development and the differentiation of MAIT1 and MAIT17.Cellular & molecular immunology · 2023Article
- Divergent metabolic programmes control two populations of MAIT cells that protect the lung.Nature cell biology · 2023Article
- Canine peripheral blood TCRαβ T cell atlas: Identification of diverse subsets including CD8AFrontiers in immunology · 2023Article
- Relevant mechanisms of MAIT cells involved in the pathogenesis of periodontitis.Frontiers in cellular and infection microbiology · 2023Review
- Gut Microbiota-Derived Unconventional T Cell Ligands: Contribution to Host Immune Modulation.ImmunoHorizons · 2022Article
- Mucosal-Associated Invariant T (MAIT) cells are highly activated in duodenal tissue of humans with Vibrio cholerae O1 infection: A preliminary report.PLoS neglected tropical diseases · 2022Article
- Circulating CD8Clinical & translational immunology · 2022Article
- Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition).European journal of immunology · 2021Review
- Multiomic analysis reveals decidual-specific transcriptional programing of MAIT cells.American journal of reproductive immunology (New York, N.Y. : 1989) · 2021Article
- Defining T Cell Subsets in Human Tonsils Using ChipCytometry.Journal of immunology (Baltimore, Md. : 1950) · 2021Article
- Gut microbiota-derived metabolites in the regulation of host immune responses and immune-related inflammatory diseases.Cellular & molecular immunology · 2021Review
- Mitochondrial metabolism is essential for invariant natural killer T cell development and function.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Human endometrial MAIT cells are transiently tissue resident and respond to Neisseria gonorrhoeae.Mucosal immunology · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mucosal-associated invariant T (MAIT) cells develop in the thymus and migrate into the periphery to become the largest antigen-specific αβ T-cell population in the human immune system. However, the frequency of MAIT cells varies widely between human individuals, and the basis for this is unclear. While MAIT cells are highly conserved through evolution and are phenotypically similar between humans and mice, they represent a much smaller proportion of total T cells in mice. In this review, we discuss how MAIT cells transition through a three-stage development pathway in both mouse and human thymus, and continue to mature and expand after they leave the thymus. Moreover, we will explore and speculate on how specific factors regulate different stages of this process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.