Evidence map›Paper›PMID 29569244›Full record

ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2018

Maternal and perinatal outcomes in pregnant women with suspected Ebola virus disease in Sierra Leone, 2014.

Meghan Lyman, Jonetta Johnson Mpofu, Fatma Soud, Titilope Oduyebo, Sascha Ellington, Gabriel W Schlough, Alimamy P Koroma, Jevon McFadden, Diane Morof

Abstract read
In one paragraph

Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Ebola virus disease in pregnancy: a systematic review and meta-analysis.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2022
    Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Atypical clinical presentation of Ebola virus disease in pregnancy: Implications for clinical and public health management.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
    Article
  10. Review
  11. Clinical presentation of pregnant women in isolation units for Ebola virus disease in Sierra Leone, 2014.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2019
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 3 countries.

Meghan LymanEpidemic Intelligence Service, Center for Surveillance, Epidemiology and Laboratory Service, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Jonetta Johnson MpofuDivision of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Fatma SoudPrevention Care and Treatment Branch, Centers for Disease Control and Prevention, c/o American Embassy, Lusaka, Zambia.
Titilope OduyeboEpidemic Intelligence Service, Center for Surveillance, Epidemiology and Laboratory Service, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Sascha EllingtonDivision of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Gabriel W SchloughWest African Medical Missions Inc, Freetown, Sierra Leone.
Alimamy P KoromaMinistry of Health and Sanitation, Freetown, Sierra Leone.
Jevon McFaddenDivision of State and Local Readiness, Centers for Disease Control and Prevention assigned to the Michigan department of Community Health, Lansing, MI, USA.
Diane MorofDivision of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Centers for Disease Control and Prevention · USMichigan Department of Health and Human Services · USMinistry of Health and Sanitation · SLNational Center for Chronic Disease Prevention and Health Promotion · USNational Center for Emerging and Zoonotic Infectious Diseases · USSierra Leone Urban Research Centre · SLThe Centers · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

objectiveTo describe maternal and perinatal outcomes among pregnant women with suspected Ebola virus disease (EVD) in Sierra Leone.

methodsObservational investigation of maternal and perinatal outcomes among pregnant women with suspected EVD from five districts in Sierra Leone from June to December 2014. Suspected cases were ill pregnant women with symptoms suggestive of EVD or relevant exposures who were tested for EVD. Case frequencies and odds ratios were calculated to compare patient characteristics and outcomes by EVD status.

resultsThere were 192 suspected cases: 67 (34.9%) EVD-positive, 118 (61.5%) EVD-negative, and 7 (3.6%) EVD status unknown. Women with EVD had increased odds of death (OR 10.22; 95% CI, 4.87-21.46) and spontaneous abortion (OR 4.93; 95% CI, 1.79-13.55) compared with those without EVD. Women without EVD had a high frequency of death (30.2%) and stillbirths (65.9%). One of 14 neonates born following EVD-negative and five of six neonates born following EVD-positive pregnancies died.

conclusionEVD-positive and EVD-negative women with suspected EVD had poor outcomes, highlighting the need for increased attention and resources focused on maternal and perinatal health during an urgent public health response. Capturing pregnancy status in nationwide surveillance of EVD can help improve understanding of disease burden and design effective interventions.

Indexed as

Pregnancy OutcomeAdolescentAdultFemaleHemorrhagic Fever, EbolaHumansInfant, NewbornPregnancyPregnancy Complications, InfectiousSierra LeoneYoung AdultEbola virus diseaseMaternal healthMortalityPerinatal outcomesSierra LeoneSpontaneous abortionStillbirthWest Africa

Identifiers

PMID29569244
PMCPMC6377193
OpenAlexW2806777104

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.