ArticleCognitive, affective & behavioral neuroscience2018
Dopamine D2 agonist affects visuospatial working memory distractor interference depending on individual differences in baseline working memory span.
Article in Cognitive, affective & behavioral neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 34 citations in OpenAlex.
- Modeling relationships between iron status, behavior, and brain electrophysiology: evidence from a randomized study involving a biofortified grain in Indian adolescents.BMC public health · 2022Trial
- Caffeine and attentional control: improved and impaired performance in healthy older adults and Parkinson's disease according to task demands.Psychopharmacology · 2022Trial
- Eye behavior does not adapt to expected visual distraction during internally directed cognition.PloS one · 2018Trial
- Detrimental effects of atomoxetine on visual signal detection in rats: comparison with ADHD psychomotor stimulant drugs.Psychopharmacology · 2026Article
- Article
- Serotonin enhances neurogenesis biomarkers, hippocampal volumes, and cognitive functions in Alzheimer's disease.Molecular brain · 2024Article
- Dopamine Increases Accuracy and Lengthens Deliberation Time in Explicit Motor Skill Learning.eNeuro · 2024Article
- Medial Prefrontal Cortex Dysfunction Mediates Working Memory Deficits in Patients With Schizophrenia.Biological psychiatry global open science · 2023Article
- Effects of cholinesterase inhibition on attention and working memory in Lewy body dementias.Brain communications · 2023Article
- A ventral stream-prefrontal cortex processing cascade enables working memory gating dynamics.Communications biology · 2022Article
- A mosaic of cost-benefit control over cortico-striatal circuitry.Trends in cognitive sciences · 2021Review
- Distraction in Visual Working Memory: Resistance is Not Futile.Trends in cognitive sciences · 2021Review
- Conscious perception and the modulatory role of dopamine: no effect of the dopamine D2 agonist cabergoline on visual masking, the attentional blink, and probabilistic discrimination.Psychopharmacology · 2020Article
- Individual differences in baseline oculometrics: Examining variation in baseline pupil diameter, spontaneous eye blink rate, and fixation stability.Cognitive, affective & behavioral neuroscience · 2019Article
- Dopamine affects short-term memory corruption over time in Parkinson's disease.NPJ Parkinson's disease · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
The interplay of dopaminergic striatal D1-D2 circuits is thought to support working memory (WM) by selectively filtering information that is to be remembered versus information to be ignored. To test this theory, we conducted an experiment in which healthy participants performed a visuospatial working memory (VSWM) task after ingesting the D2-receptor agonist cabergoline (or placebo), in a randomized, double-blinded, crossover design. Results showed greater interference from distractors under cabergoline, particularly for individuals with higher baseline dopamine (indicated by WM span). These findings support computational theories of striatal D1-D2 function during WM encoding and distractor-filtering, and provide new evidence for interactive cortico-striatal systems that support VSWM capacity and their dependence on WM span.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.