Evidence map›Paper›PMID 29569164›Full record

ReviewTargeted oncology2018

Prognostic and Predictive Factors for Renal Cell Carcinoma.

Cristina Suárez, Marc Campayo, Romà Bastús, Sergi Castillo, Olatz Etxanitz, Marta Guix, Núria Sala, Enrique Gallardo

Abstract readReview
PubMed Publisher
In one paragraph

Review in Targeted oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Cristina SuárezVall d'Hebron University Hospital and Institute of Oncology, Universitat Autònoma de Barcelona, Barcelona, Spain.
Marc CampayoOncology Department, Hospital Universitary Mútua Terrassa, Terrassa, Barcelona, Spain.
Romà BastúsOncology Department, Hospital Universitary Mútua Terrassa, Terrassa, Barcelona, Spain.
Sergi CastilloOncology Department, Hospital de Granollers, Granollers, Barcelona, Spain.
Olatz EtxanitzOncology Department, Institut Català d'Oncologia, Hospital Germans Trias i Pujol, Badalona, Barcelona, Spain.
Marta GuixOncology Department, Hospital del Mar, Barcelona, Spain.
Núria SalaOncology Department, Institut Català d'Oncologia, Hospital Josep Trueta, Girona, Spain.
Enrique GallardoOncology Department, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí I3PT, Universitat Autònoma de Barcelona, Sabadell, Spain. egallardo@tauli.cat.ORCID 0000-0002-1375-3488
Institut Català d'Oncologia · ESMútua Terrassa · ESUniversitat Autònoma de Barcelona · ESHospital Del Mar · ESHospital General de Granollers · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metastatic renal cell carcinoma (mRCC) is an incurable malignancy, characterized by its resistance to traditional chemotherapy, radiation, and hormonal therapy. Treatment perspectives and prognosis of patients with mRCC have been significantly improved by advances in the understanding of its molecular pathogenesis, which have led to the development of targeted therapeutics. Different molecular factors derived from the tumor or the host detected in both tissue or serum could be predictive of therapeutic benefit. Some of them suggest a rational selection of patients to be treated with certain therapies, though none have been validated for routine use. This article provides an overview of both clinical and molecular factors associated with predictive or prognostic value in mRCC and emphasizes that both should be considered in parallel to provide the most appropriate, individualized treatment and achieve the best outcomes in clinical practice.

Indexed as

Carcinoma, Renal CellHumansKidney NeoplasmsPrognosis

Identifiers

PMID29569164
OpenAlexW2789792494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.