Evidence map›Paper›PMID 29569087›Full record

ArticleInternational ophthalmology2018

Reversal of retinal pigment epithelial detachment after cessation of topical travoprost therapy.

Venkataramana Kalikivayi, Jerry Joseph, Blessy Thankom Mathews, Rajkumar Maheswari, Satyajit Mulanjur Vadakara, Sajeev Cherian Jacob

Abstract readCase Reports
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In one paragraph

Article in International ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Venkataramana KalikivayiAhalia School of Optometry, Ahalia Foundation Eye Hospital, Kozhipara Post, Palakkad, Kerala, India. kalikivayi@yahoo.com.
Jerry JosephAhalia Foundation Eye Hospital, Kozhipara Post, Palakkad, Kerala, India.
Blessy Thankom MathewsAhalia Foundation Eye Hospital, Kozhipara Post, Palakkad, Kerala, India.
Rajkumar MaheswariAhalia Foundation Eye Hospital, Kozhipara Post, Palakkad, Kerala, India.
Satyajit Mulanjur VadakaraAhalia Foundation Eye Hospital, Kozhipara Post, Palakkad, Kerala, India.
Sajeev Cherian JacobAhalia Foundation Eye Hospital, Kozhipara Post, Palakkad, Kerala, India.
ACT Foundation · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo report the rare incidence of retinal pigment epithelial detachment (RPED) followed by topical travoprost therapy and its subsequent reattachment after cessation of the drug.

methodsA 60-year-old male presented with gradual loss of vision in both eyes and distorted images in right eye. He gave a history of visiting an ophthalmologist a week ago for a routine eye examination. His previous reports revealed best-corrected visual acuity (BCVA) of 6/6, N6 in both eyes with raised intraocular pressures. A diagnosis of primary open-angle glaucoma was made and prescribed topical travoprost 0.004% eye drops. This patient's subsequent visit with diagnosis and treatment is mentioned in this case report.

resultsOn examination, his BCVA was found to be 6/36, N12 and 6/6, N6 in right and left eyes, respectively. Optical coherence tomography (OCT) macular scan revealed RPED involving fovea in the right eye and inferotemporal to fovea in the left eye. Patient was advised to discontinue topical travoprost and started brinzolamide 1% eye drops. Ten-day follow-up visit revealed partially resolved RPED by OCT with 6/9 and 6/6 visual acuity in the right and left eyes, respectively. After 1 month, reversal of RPED was noted in OCT with 6/6 vision in both eyes.

conclusionHence, clinicians should be aware of this rare incidence of RPED followed by travoprost therapy. First case of RPED following travoprost therapy and complete reattachment upon withdrawal is reported here in this case report.

Indexed as

Visual AcuityAdministration, TopicalAntihypertensive AgentsFluorescein AngiographyFundus OculiGlaucomaHumansMaleMiddle AgedRetinal DetachmentRetinal Pigment EpitheliumTomography, Optical CoherenceTravoprostWithholding TreatmentAntihypertensive AgentsTravoprostIntraocular pressureProstaglandin analoguesRetinal pigment epithelial detachmentTravoprost

Identifiers

PMID29569087
OpenAlexW2791299912

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.