ReviewClinical neuroradiology2019
Posterior Circulation Occlusions May Be Associated with Distal Emboli During Thrombectomy : Factors for Distal Embolization and a Review of the Literature.
Review in Clinical neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Efficacy and safety of thrombectomy with or without intravenous thrombolysis in the treatment of acute basilar artery occlusion ischemic stroke: an updated systematic review and meta-analysis.Frontiers in neurology · 2024Pooled it
- Endovascular Therapy in Acute Isolated Posterior Cerebral Artery Occlusion : Systematic Review and Meta-analysis.Clinical neuroradiology · 2023Pooled it
- Endovascular treatment with or without intravenous alteplase for acute ischaemic stroke due to basilar artery occlusion.Stroke and vascular neurology · 2022Pooled it
- Impact of Balloon Guide Catheter on Thrombectomy Outcomes in Intracranial Carotid Artery Embolic Occlusion: A Retrospective Cohort Study.Stroke (Hoboken, N.J.) · 2026Article
- Predictors of distal embolization during thrombectomy for anterior circulation large vessel bifurcation occlusion stroke.Journal of neurointerventional surgery · 2025Article
- Development, characterization, and curve fitting of rate-dependent models of calcified cerebral embolus analogs for acute ischemic stroke.Biomechanics and modeling in mechanobiology · 2025Article
- Endovascular structures of the basilar artery as forms of the basilar nonfusion spectrum.Scientific reports · 2025Article
- Purtscher-like retinopathy following mechanical thrombectomy: A case report.SAGE open medical case reports · 2025Article
- Safety and efficacy of continuous intra-arterial infusion of heparin administration in mechanical thrombectomy for acute ischemic stroke: a single-center retrospective study.Frontiers in neurology · 2025Article
- Bilateral Oculomotor Nerve Palsy: A Rare Complication of Bridging Thrombolysis for Acute Basilar Artery Occlusion.International medical case reports journal · 2025Article
- Novel use of a stent retriever as a distal filler protection device for prevention of secondary embolization.Journal of cerebrovascular and endovascular neurosurgery · 2024Article
- Predictors of Emboli in Mechanical Thrombectomy for Anterior Circulation Stroke.Current neurovascular research · 2024Article
- A Review of Endovascular Treatment for Posterior Circulation Strokes.Neurointervention · 2023Review
- Short-term efficacy of stenting as a rescue therapy for acute atherosclerotic occlusion in anterior cerebral circulation.Frontiers in neurology · 2023Article
- Percutaneous transluminal angioplasty and stenting in acute stroke caused by basilar artery steno-occlusive disease: The experience of a single stroke centre.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022Article
- What You Always Wanted to Know about Endovascular Therapy in Acute Ischemic Stroke but Never Dared to Ask: A Comprehensive Review.Reviews in cardiovascular medicine · 2022Review
- Endovascular Treatment for Posterior Circulation Stroke: Ways to Maximize Therapeutic Efficacy.Journal of stroke · 2022Review
- Transcirculation Embolization to New Territory During Mechanical Thrombectomy for Acute Ischemic Stroke.The Neurohospitalist · 2022Article
- Comparing the Conventional and Balloon-Guided Catheter-Assisted SWIM Technology for the Treatment of Acute Ischemic Stroke.Frontiers in neurology · 2022Article
- Stroke thrombectomy complication management.Journal of neurointerventional surgery · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDistal embolization or movement of the thrombus to previously uninvolved vasculature are feared complications during stroke thrombectomy. We looked at associated factors in a consecutive series of patients who underwent thrombectomy with the same endovascular device.
methodsWe included all patients with acute ischemic stroke in the anterior or posterior circulation, who underwent thrombectomy with the same thrombectomy device for acute stroke from 2013 to 2016. Distal embolization was defined as any movement of the thrombus into a previously uninvolved portion of the cerebral vasculature or the presence of thrombotic material further downstream in the affected vessel, which occurred after the initial angiogram. We studied patient-related as well as technical factors to determine their association with distal emboli.
resultsIn this study 167 consecutive acute stroke patients treated with the emboTrap® device (Cerenovus, Irvine, CA, USA) were included with a median National Institutes of Health Stroke Scale (NIHSS) of 15 (range 2-30) and mean age of 67 years (SD 13.1 years). Of the patients in our cohort 20 (11.9%) experienced distal emboli, with 2.3% into a new territory and 9.6% into a territory distal to the primary occlusion. On univariate analysis, age, intravenous tissue plasminogen activator (tPA), posterior circulation occlusions, and general anesthesia were associated with distal emboli. On multivariate analysis, only posterior circulation occlusions (odds ratio OR 4.506 95% confidence interval CI 1.483-13.692, p = 0.008) were significantly associated with distal emboli. Distal embolization was not significantly associated with worse functional outcomes at 3 months, increased mortality or increased bleeding risk.
conclusionPosterior circulation occlusions were significantly associated with distal emboli during thrombectomy, possibly due to the lack of flow arrest during such procedures. New techniques and devices should be developed to protect against embolic complications during posterior circulation stroke thrombectomy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.