Evidence map›Paper›PMID 29568972›Full record

ReviewSeminars in immunopathology2018

Innate lymphoid cells in autoimmunity and chronic inflammatory diseases.

Tingting Xiong, Jan-Eric Turner

Abstract readReview
PubMed Publisher
In one paragraph

Review in Seminars in immunopathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 36 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Activation of GABAAntioxidants (Basel, Switzerland) · 2024
    Article
  6. Review
  7. Review
  8. The role of CD56Journal of neuroinflammation · 2024
    Review
  9. Macrophages as potential targets in gene therapy for cancer treatment.Exploration of targeted anti-tumor therapy · 2023
    Review
  10. Article
  11. Review
  12. Circulating CCR6Clinical & translational immunology · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Innate Lymphoid Cells in Renal Inflammation.Frontiers in immunology · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Tingting XiongIII. Medizinische Klinik, Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.
Jan-Eric TurnerIII. Medizinische Klinik, Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany. j.turner@uke.de.
Martini-Klinik · DEUniversity Medical Center Hamburg-Eppendorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abnormal activation of the innate immune system is a common feature of autoimmune and chronic inflammatory diseases. Since their identification as a separate family of leukocytes, innate lymphoid cells (ILCs) have emerged as important effector cells of the innate immune system. Alterations in ILC function and subtype distribution have been observed in a variety of immune-mediated diseases in humans and evidence from experimental models suggests a subtype specific role of ILCs in the pathophysiology of autoimmune inflammation. In this review, we discuss recent advances in the understanding of ILC biology in autoimmune and chronic inflammatory disorders, including multiple sclerosis, inflammatory bowel diseases, psoriasis, and rheumatic diseases, with a special focus on the potential of ILCs as therapeutic targets for the development of novel treatment strategies in humans.

Indexed as

AutoimmunityImmunity, InnateAnimalsAutoimmune DiseasesBiomarkersChronic DiseaseCytokinesDisease SusceptibilityGene Expression RegulationHumansInflammationInflammation MediatorsLymphocyte SubsetsSignal TransductionBiomarkersCytokinesInflammation MediatorsAutoimmune diseaseInflammatory bowel diseaseInnate lymphoid cellsMultiple sclerosisPsoriasisRheumatic disease

Identifiers

PMID29568972
OpenAlexW2789368077

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.