Evidence map›Paper›PMID 29568850›Full record

ArticleSingapore medical journal2018

Medication-related osteonecrosis of the jaw in osteoporotic patients: prevention and management.

Boon Hui Chan, Ruixiang Yee, Rukshini Puvanendran, Seng Bin Ang

Abstract read
In one paragraph

Article in Singapore medical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  13. Managing tooth pain in general practice.Singapore medical journal · 2019
    Article
  14. Hip fractures in Singapore: ethnic differences and temporal trends in the new millennium.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Boon Hui ChanDental Service, KK Women's and Children's Hospital, Singapore.
Ruixiang YeeDental Service, KK Women's and Children's Hospital, Singapore.
Rukshini PuvanendranFamily Medicine Service, KK Women's and Children's Hospital, Singapore.
Seng Bin AngFamily Medicine Service, KK Women's and Children's Hospital, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoporosis is a major, growing healthcare issue. This is especially of concern in an ageing population like that of Singapore. Osteoporotic patients are at risk of fractures, which can result in increased morbidity and mortality. The use of antiresorptive therapy with bisphosphonates or denosumab has been proven to reduce fracture risk. However, the use of these medications has rarely been associated with the development of osteonecrosis of the jaw, a potentially debilitating condition affecting one or both jaws. Appropriate understanding of the patient's antiresorptive therapy regime, as well as early institution of preventive dental measures, can play an important role in preventing medication-related osteonecrosis of the jaw (MRONJ). Regular monitoring and prompt referral to specialist care is warranted for patients with established MRONJ.

Indexed as

AgedBone Density Conservation AgentsDenosumabDiphosphonatesHumansJaw DiseasesOsteonecrosisOsteoporosisOsteoporotic FracturesRisk FactorsSingaporeTreatment OutcomeBone Density Conservation AgentsDenosumabDiphosphonatesbisphosphonatesMRONJosteonecrosisosteoporosis

Identifiers

PMID29568850
PMCPMC6119741

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.