Evidence map›Paper›PMID 29568765›Full record

ArticleBioMed research international2018

The Potential Protective Effect of Curcumin on Amyloid-

Lu Zhang, Yu Fang, Xuan Cheng, Yajun Lian, Zhaoshu Zeng, Chuanjie Wu, Hongcan Zhu, Hongliang Xu

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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  7. Review
  8. Neuro-Nutraceutical Polyphenols: How Far Are We?Antioxidants (Basel, Switzerland) · 2023
    Review
  9. Curcumin effect onPeerJ · 2022
    Article
  10. Review
  11. Review
  12. Article
  13. Natural Compounds and Autophagy: Allies Against Neurodegeneration.Frontiers in cell and developmental biology · 2020
    Review
  14. Article
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lu ZhangDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Yu FangDepartment of Intensive Care Unit, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.ORCID 0000-0002-5169-364X
Xuan ChengDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Yajun LianDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Zhaoshu ZengDepartment of Legal Medicine, The College of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China.
Chuanjie WuDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Hongcan ZhuDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Hongliang XuDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
First Affiliated Hospital of Zhengzhou University · CNZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to investigate the effect and mechanism of curcumin (CUR) in Alzheimer's disease (AD).

methodsMouse hippocampal neuronal cell line HT-22 was treated with A

resultsA

conclusionsCUR might have a potential neuroprotective effect by promoting cell viability in AD, which might be associated with cell autophagy. Furthermore, MYC, Cdh1, and Acaca might be involved in the progression of AD.

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAnimalsAutophagyCell LineCell SurvivalCurcuminHippocampusMiceNeuronsNeuroprotective AgentsPeptide FragmentsTranscriptomeAmyloid beta-PeptidesCurcuminNeuroprotective AgentsPeptide Fragments

Identifiers

PMID29568765
PMCPMC5820551
OpenAlexW2783064097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.