Evidence map›Paper›PMID 29568732›Full record

ArticleFrontiers in cellular and infection microbiology2018

Role of Murine Complement Component C5 in Acute

Íris A de Castro, Lorena Bavia, Tatiana R Fraga, Mariane T Amano, Leandro C D Breda, Adriana P Granados-Martinez, Ana M G da Silva, Silvio A Vasconcellos, Lourdes Isaac

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Unveiling the impact ofInfection and immunity · 2024
    Article
  3. Article
  4. Article
  5. Understanding the Renal Fibrotic Process in Leptospirosis.International journal of molecular sciences · 2021
    Review
  6. Cytokine Profile in Early Infection byJournal of immunology research · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Íris A de CastroLaboratory of Complement, Department of Immunology, University of São Paulo, São Paulo, Brazil.
Lorena BaviaLaboratory of Complement, Department of Immunology, University of São Paulo, São Paulo, Brazil.
Tatiana R FragaLaboratory of Complement, Department of Immunology, University of São Paulo, São Paulo, Brazil.
Mariane T AmanoLaboratory of Complement, Department of Immunology, University of São Paulo, São Paulo, Brazil.
Leandro C D BredaLaboratory of Complement, Department of Immunology, University of São Paulo, São Paulo, Brazil.
Adriana P Granados-MartinezLaboratory of Complement, Department of Immunology, University of São Paulo, São Paulo, Brazil.
Ana M G da SilvaInstitute of Tropical Medicine, University of São Paulo, São Paulo, Brazil.
Silvio A VasconcellosFaculty of Veterinary Medicine, University of São Paulo, São Paulo, Brazil.
Lourdes IsaacLaboratory of Complement, Department of Immunology, University of São Paulo, São Paulo, Brazil.
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leptospirosis is considered one of the most important zoonosis worldwide. The activation of the Complement System is important to control dissemination of several pathogens in the host. Only a few studies have employed murine models to investigate leptospiral infection and our aim in this work was to investigate the role of murine C5 during

Indexed as

AnimalsComplement C5CytokinesDisease Models, AnimalInflammationInterleukin-10KidneyLeptospira interrogansLeptospirosisLeukocytesLiverMiceMice, Inbred C57BLMice, Mutant StrainsSpleenSurvival AnalysisComplement C5CytokinesInterleukin-10C5Complement SysteminflammationLeptospiraleptospirosismurine model

Identifiers

PMID29568732
PMCPMC5852101
OpenAlexW2792395545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.