Evidence map›Paper›PMID 29568728›Full record

ArticleWorld journal of psychiatry2018

Repeatability of two-dimensional chemical shift imaging multivoxel proton magnetic resonance spectroscopy for measuring human cerebral choline-containing compounds.

Basant K Puri, Mary Egan, Fintan Wallis, Philip Jakeman

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Article in World journal of psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Basant K PuriDepartment of Medicine, Hammersmith Hospital, Imperial College London, London W12 0HS, United Kingdom.
Mary EganDepartment of Radiology, University Hospital Limerick, Limerick V94 YVH0, Ireland.
Fintan WallisDepartment of Radiology, University Hospital Limerick, Limerick V94 YVH0, Ireland.
Philip JakemanCentre for Interventions in Infection, Inflammation and Immunity, University of Limerick, Limerick V94 PX58, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the repeatability of proton magnetic resonance spectroscopy in the

methodsTwo consecutive scans were carried out in six healthy resting subjects at a magnetic field strength of 1.5 T. On each occasion, neurospectroscopy data were collected from 64 voxels using the same 2D chemical shift imaging (CSI) sequence. The data were analyzed in the same way, using the same software, to obtain the values for each voxel of the ratio of Cho to creatine. The Wilcoxon related-samples signed-rank test, coefficient of variation (CV), repeatability coefficient (RC), and intraclass correlation coefficient (ICC) were used to assess the repeatability.

resultsThe CV ranged from 2.75% to 33.99%, while the minimum RC was 5.68%. There was excellent reproducibility, as judged by significant ICC values, in 26 voxels. Just three voxels showed significant differences according to the Wilcoxon related-samples signed-rank test.

conclusionIt is therefore concluded that when CSI multivoxel proton neurospectroscopy is used to measure cerebral choline-containing compounds at 1.5 T, the reproducibility is highly acceptable.

Indexed as

Cerebral metabolitesChemical shift imagingCholineNeuropsychiatric disordersNeurospectroscopy

Identifiers

PMID29568728
PMCPMC5862651

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