ArticlePeerJ2018
Gender, age, and concomitant diseases of melanosis coli in China: a multicenter study of 6,090 cases.
Article in PeerJ, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Colorectal neoplasms in melanosis coli: a survey in Japan and a worldwide meta-analysis.International journal of colorectal disease · 2021Pooled it
- A self-reported symptom-based decision-making model helps to rule out outpatient cases at low risk for CRC before colonoscopy.Heliyon · 2024Article
- Colonoscopic Resolution of Melanosis Coli After Cessation of Senna Laxative Use.International medical case reports journal · 2024Article
- Review on melanosis coli and anthraquinone-containing traditional Chinese herbs that cause melanosis coli.Frontiers in pharmacology · 2023Review
- Intraoperative discovery of melanosis coli during emergent bowel resection for perforation.BMJ case reports · 2022Article
- Melanosis coli: A factor not associated with histological progression of colorectal polyps.Journal of digestive diseases · 2022Article
- Case report: Melanosis coli combined with colon cancer, causality or coincidence?Frontiers in surgery · 2022Article
- Melanosis coli in a peritoneal dialysis patient: a case report.Journal of medical case reports · 2021Article
- Melanosis Coli.JMA journal · 2021Article
- The association between the socioeconomic status and systemic comorbidities in patients with oral cancers: a retrospective study in Guangxi Province.Clinical oral investigations · 2021Article
- Melanosis Coli Due to Aloe Vera Consumption.Internal medicine (Tokyo, Japan) · 2020Article
- Retrospective study on melanosis coli as risk factor of colorectal neoplasm: a 3-year colonoscopic finding in Zhuhai Hospital, China.International journal of colorectal disease · 2020Article
- Differential proteomics mass spectrometry of melanosis coli.American journal of translational research · 2020Review
- Identification of candidate biomarkers associated with apoptosis in melanosis coli: GNG5, LPAR3, MAPK8, and PSMC6.Bioscience reports · 2019Article
Corrections and comments
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Authors and funding
13 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUNDS AND
aimsMelanosis coli (MC) is a noninflammatory, benign, and reversible colonic disorder, but its detection rates in China are unclear. We therefore aimed to analyze the epidemiological characteristics of MC in China.
methodsWe assessed the detection rates, associated factors and concomitant diseases of MC in the patients who underwent colonoscopy at eight medical centers across five regions of China between January 2006 and October 2016. All data were procured from the electronic database established at each participating institutions.
resultsAmong the 342,922 included cases, MC was detected in 6,090 cases (detection rate = 1.78%, 95% confidence interval, 1.73%-1.82%) at a mean age of 60 years. The detection rate gradually increased yearly, and along with the increasing age regardless of gender, while a rapid increase presented in the patients ≥60 years of age (0.58% for ≤25 years, 1.22% for 25-59 years, and 3.19% for ≥60 years). The detection rate was higher in females than in males; however, the rate of per-year increase was higher in males than in females at age of ≥60 years, which was 1.85-fold of that in females. Among cancer, polyp, inflammation, and diverticula, polyp was the most common concomitant disease of MC and identified in 41.72% of MC patients.
conclusionsMC detection rates were increased annually and elevated in older patients, particularly in male patients. Males in the elderly population of ≥60 years were most likely to have MC. Colonic polyp is the most common concomitant disease of MC.
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