ArticleBrain and behavior2018
Effects of gender, digit ratio, and menstrual cycle on intrinsic brain functional connectivity: A whole-brain, voxel-wise exploratory study using simultaneous local and global functional connectivity mapping.
Article in Brain and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Sex differences in brain homotopic co-activations: a meta-analytic study.Brain structure & function · 2022Pooled it
- Evidence for a robust, estradiol-associated sex difference in narrative-writing fluency.Neuropsychology · 2021Pooled it
- Gender and cytoarchitecture differences: Functional connectivity of the hippocampal sub-regions.Heliyon · 2023Article
- Transmit Radiant Individuality to Offspring (TRIO) study: investigating intergenerational transmission effects on brain development.Frontiers in psychiatry · 2023Article
- Hormone-based models for comparing menstrual cycle and hormonal contraceptive effects on human resting-state functional connectivity.Frontiers in neuroendocrinology · 2022Article
- Inter-Network Brain Functional Connectivity in Adolescents Assigned Female at Birth Who Experience Gender Dysphoria.Frontiers in endocrinology · 2022Article
- Ovarian steroid hormones: A long overlooked but critical contributor to brain aging and Alzheimer's disease.Frontiers in aging neuroscience · 2022Review
- Premenstrual dysphoric disorder is associated with the longer length from clitoris to urethra.BMC women's health · 2021Article
- Regional abnormality of functional connectivity is associated with clinical manifestations in individuals with intractable focal epilepsy.Scientific reports · 2021Article
- Increased Global-Brain Functional Connectivity Is Associated with Dyslipidemia and Cognitive Impairment in First-Episode, Drug-Naive Patients with Bipolar Disorder.Neural plasticity · 2021Article
- Global Functional Connectivity Analysis Indicating Dysconnectivity of the Hate Circuit in Major Depressive Disorder.Frontiers in aging neuroscience · 2021Article
- Increased large-scale inter-network connectivity in relation to impulsivity in Parkinson's disease.Scientific reports · 2020Article
- Article
- Effects of gender, digit ratio, and menstrual cycle on intrinsic brain functional connectivity: A whole-brain, voxel-wise exploratory study using simultaneous local and global functional connectivity mapping.Brain and behavior · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Gender and sex hormones influence brain function, but their effects on functional network organization within the brain are not yet understood. Methods: We investigated the influence of gender, prenatal sex hormones (estimated by the 2D:4D digit ratio), and the menstrual cycle on the intrinsic functional network organization of the brain (as measured by 3T resting-state functional MRI (rs-fMRI)) using right-handed, age-matched university students (100 males and 100 females). The mean (± Results: There was a significant difference between the male mean map and female mean map in the distributions of network properties in almost all cortical regions and the basal ganglia but not in the medial parietal, limbic, and temporal regions and the thalamus. A comparison between the mean map for the low 2D:4D digit ratio group (indicative of high exposure to testosterone during the prenatal period) and that for the high 2D:4D digit ratio group revealed a significant difference in the network properties of the medial parietal region for males and in the temporal region for females. The menstrual cycle affected network organization in the brain, which varied with the 2D:4D digit ratio. Most of these findings were reproduced with our other datasets created with different preprocessing steps. Conclusions: The results suggest that differences in gender, prenatal sex hormone exposure, and the menstrual cycle are useful for understanding the normal brain and investigating the mechanisms underlying the variable prevalence and symptoms of neurological and psychiatric diseases.
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